Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13798757 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL18651110 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL10331462 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL775818 | 0.80 | SMN1; SMN2 (0.35) | SMN1; SMN2CA14CA12DPP4 | |
| SCHEMBL23786850 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL31111331 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL28738654 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL15777140 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL9763405 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL3147895 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104974600-A | Water-in-water multicolor pattern paint | SUZHOU SHUERSHI TEXTILE NEW MATERIAL TECHNOLOGY CO LTD | 2015-10-14 | — | — | CN | claimed |
| US-20230381182-A1 | Biomarkers Related to Immune Checkpoint Inhibitor Therapy and Methods of Using the Same | SAIL BIOMEDICINES, INC. | 2023-11-30 | — | — | US | disclosed |
| US-20230295152-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AS AHR ANTAGONISTS | SENDA BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| CN-109952360-B | Quantum dot dispersion, self-luminous photosensitive resin composition, color filter manufactured using the same, and image display device | 东友精细化工有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-106432365-B | Ferrocenyl compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically unsaturated compounds | 赢创运营有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-109810589-A | Light converts resin combination, light conversion layer folds substrate and image display device | 东友精细化工有限公司 | 2019-05-28 | — | — | CN | disclosed |
| US-10077228-B2 | Ferrocene-based compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically unsaturated compounds | EVONIK DEGUSSA GMBH (DE) | 2018-09-18 | — | — | US | disclosed |
| EP-3121186-B1 | FERROCENE-BASED COMPOUNDS AND PALLADIUM CATALYSTS BASED ON SAME FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2018-09-12 | — | — | EP | disclosed |
| US-20180022765-A1 | PROCESS FOR THE ALKOXYCARBONYLATION OF ALCOHOLS | EVONIK DEGUSSA GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180022765-A1 | PROCESS FOR THE ALKOXYCARBONYLATION OF ALCOHOLS | EVONIK DEGUSSA GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-8778941-B2 | TRPM8 antagonists and their use in treatments | AMGEN INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140030609-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND ENERGY STORAGE DEVICE USING SAME | UBE INDUSTRIES, LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| CN-103477492-A | Non-aqueous electrolyte solution and electricity-storage device using same | UBE INDUSTRIES | 2013-12-25 | — | — | CN | disclosed |
| US-20130158034-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-8354403-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120157432-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME, CORP. (US) | 2012-06-21 | — | — | US | disclosed |
| US-8084395-B2 | 4-aza indole derivatives and their use as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100184598-A1 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-22 | — | — | US | disclosed |
| US-6066666-A | OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX | WASHINGTON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |
| US-5776959-A | Anticonvulsant and anxiolytic lactam and thiolactam derivatives | WASHINGTON UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295152-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AS AHR ANTAGONISTS | AHR, ARNT, AIPL1 | SMN1; SMN2 4669/4885CA14 4857/4885CA12 4844/4885 |
| US-20130158034-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | TRPM8, TRPM7, TRPM5 | SMN1; SMN2 837/4885CA14 2616/4885CA12 2722/4885 |
| US-10077228-B2 | Ferrocene-based compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically unsaturated compounds | C5, C1S, ALOX12 | SMN1; SMN2 3811/4885CA14 2232/4885CA12 755/4885 |
| US-20230381182-A1 | Biomarkers Related to Immune Checkpoint Inhibitor Therapy and Methods of Using the Same | AHR, CD274, ARNT | SMN1; SMN2 3152/4885CA14 2834/4885CA12 2903/4885 |
| US-20180022765-A1 | PROCESS FOR THE ALKOXYCARBONYLATION OF ALCOHOLS | ADH1C, ADH1A, C1S | SMN1; SMN2 3449/4885CA14 1457/4885CA12 807/4885 |
| US-20120157432-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | ADRB3, ADRB1, ADRB2 | SMN1; SMN2 3655/4885CA14 4885/4885CA12 4876/4885 |
| US-20100184598-A1 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | IDO1, INMT, AZI2 | SMN1; SMN2 4466/4885CA14 1437/4885CA12 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.