⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443681 | 0.81 | CTSC (0.40) | — | |
| SCHEMBL18342496 | 0.78 | ACACB (0.33) | — | |
| SCHEMBL21724531 | 0.78 | HDAC3 (0.40) | — | |
| SCHEMBL3520934 | 0.76 | CA2 (0.43) | — | |
| SCHEMBL5053530 | 0.76 | NFKB1 (0.34) | — | |
| SCHEMBL4599052 | 0.76 | NFKB1 (0.34) | — | |
| SCHEMBL4599093 | 0.76 | NFKB1 (0.34) | — | |
| SCHEMBL6798837 | 0.75 | TERT (0.33) | — | |
| SCHEMBL21724578 | 0.74 | FAAH (0.53) | — | |
| SCHEMBL21724576 | 0.72 | FAAH (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361329-B2 | Compositions for inducing an immune response | CHEMOCENTRYX, INC. (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1274454-B1 | METHODS AND COMPOSITIONS FOR ELICITING AN IMMUNE RESPONSE | CHEMOCENTRYX INC (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20030108515-A1 | Methods and compositions for inducing an immune response | CHEMOCENTRYX, INC. | 2003-06-12 | — | — | US | disclosed |
| WO-2003035106-A1 | METHODS AND COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE BY CO-ADMINISTERING A CHEMOKINE WITH AN ANTIGEN | CHEMOCENTRYX (US) | 2003-05-01 | — | — | WO | disclosed |
| EP-1274454-A2 | METHODS AND COMPOSITIONS FOR ELICITING AN IMMUNE RESPONSE | Chemocentryx, Inc. (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2002085409-A2 | METHODS AND COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE TO AN ANTIGEN | CHEMOCENTRYX (US) | 2002-10-31 | — | — | WO | disclosed |
| US-20020071825-A1 | Methods and compositions for inducing an immune response | CHEMOCENTRYX, INC. | 2002-06-13 | — | — | US | disclosed |
| WO-2001080882-A2 | METHODS AND COMPOSITIONS FOR ELICITING AN IMMUNE RESPONSE | CHEMOCENTRYX, INC (US) | 2001-11-01 | — | — | WO | disclosed |
| WO-2001080887-A2 | METHODS AND CHEMOKIN COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE | CHEMOCENTRYX, INC. (US) | 2001-11-01 | — | — | WO | disclosed |