Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20398910 | 0.86 | TSHR (0.56) | CYP1A2KMT2AALDH1A1TDP1CYP3A4 | |
| SCHEMBL11283053 | 0.86 | CYP1A2 (0.47) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL8103969 | 0.84 | TDP1 (0.49) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL10453981 | 0.82 | CYP1A2 (0.43) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL282083 | 0.81 | CYP1A2 (0.61) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL3050742 | 0.80 | CYP1A2 (0.52) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL3517667 | 0.80 | CYP1A2 (0.52) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL24597734 | 0.79 | CYP1A2 (0.59) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL7034021 | 0.79 | CYP1A2 (0.59) | CYP1A2KMT2AALDH1A1TRPA1TDP1 | |
| SCHEMBL1005765 | 0.79 | CYP1A2 (0.59) | CYP1A2KMT2AALDH1A1TRPA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375246-B2 | Sulfhydral containing compounds and methods of using the same | REGENESIS BIOREMEDIATION PRODUCTS INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-20050148712-A1 | Polyol esters of sulfhydryl carboxylic acids; treating water and water-containing soils contaminated with metal | FARONE WILLIAM A (US) | 2005-07-07 | — | — | US | disclosed |
| US-6846947-B2 | Sulfhydral containing compounds and methods of using same | REGENESIS BIOREMEDIATION PRODUCTS, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040157316-A1 | Sulfhydral containing compounds and methods of using same | REGENESIS | 2004-08-12 | — | — | US | disclosed |
| US-20040158095-A1 | Sulfhydral containing compounds and methods of using same | REGENESIS, INC. | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158095-A1 | Sulfhydral containing compounds and methods of using same | TST, QSOX1, CTH | CYP1A2 781/4885KMT2A 2232/4885ALDH1A1 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.