Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865336 | 0.83 | ESR2 (0.40) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL29006702 | 0.76 | HTT (0.44) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL4864990 | 0.75 | MAPT (0.39) | ESR2ESR1KMT2AMEN1HSD17B10 | |
| SCHEMBL30833366 | 0.74 | IDO1 (0.46) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL28657683 | 0.71 | PDE4B (0.37) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL28973790 | 0.70 | PTPN22 (0.35) | ESR2ESR1KMT2AMEN1GAA | |
| SCHEMBL4138765 | 0.69 | CA2 (0.45) | ESR1KMT2AGAAHSD17B10KDM4E | |
| SCHEMBL12737774 | 0.68 | L3MBTL1 (0.55) | KMT2AMEN1GAAHSD17B10KDM4E | |
| Toluene SCHEMBL28657685 | 0.68 | ESR1 (0.41) | ESR2ESR1KMT2AMEN1GAA | |
| Benzene SCHEMBL28642827 | 0.67 | IDO1 (0.46) | ESR2ESR1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008513585-A | — | — | 2008-05-01 | — | — | JP | claimed |
| CN-101061127-A | 1, 4-Hydroquinone functionalized phosphinites and phosphonates | CHEMTURA CORP (US) | 2007-10-24 | — | — | CN | claimed |
| EP-1791850-A1 | 1,4-HYDROQUINONE FUNCTIONALIZED PHOSPHINATES AND PHOSPHONATES | CHEMTURA CORPORATION (US) | 2007-06-06 | — | — | EP | claimed |
| US-20060099458-A1 | 1, 4-Hydroquinone functionalized phosphinates and phosphonates | HANSON MARK V | 2006-05-11 | — | — | US | claimed |
| WO-2006034445-A1 | 1,4-HYDROQUINONE FUNCTIONALIZED PHOSPHYNATES AND PHOSPHONATES | CHEMTURA CORPORATION (US) | 2006-03-30 | — | — | WO | claimed |