SCHEMBL4865575

SCHEMBL4865575

CCC(C)c1ccccc1OP(O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
KDM4E B2RXH2 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.43
NISCH Q9Y2I1 1/20 0.43
HTT P42858 2/20 0.43
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
MAPT P10636 1/20 0.35
RORC P51449 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561228 0.85 TSHR (0.52) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL10415188 0.82 TSHR (0.48) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL13160811 0.82 TSHR (0.48) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL5181579 0.81 PPARG (0.41) ALDH1A1LMNAKMT2AMAPTPPARA
SCHEMBL8060858 0.81 GABRA1 (0.45) TSHRL3MBTL1NISCHALDH1A1LMNA
SCHEMBL11983515 0.80 TSHR (0.47) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL190108 0.79 TSHR (0.59) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL13160836 0.79 TSHR (0.46) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL12362394 0.79 L3MBTL1 (0.46) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL10415190 0.79 TSHR (0.46) TSHRKDM4EL3MBTL1ATMNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104508031-B Phosphite compositions 瑞士新集团有限公司 2020-10-16 CN disclosed
EP-2880092-B1 PHOSPHITE COMPOSITIONS SI GROUP SWITZERLAND CHAA GMBH (CH) 2020-09-30 EP disclosed
EP-2880092-A1 PHOSPHITE COMPOSITIONS Addivant Switzerland GmbH (CH) 2015-06-10 EP disclosed
US-20150073073-A1 PHOSPHITE COMPOSITIONS ADDIVANT USA, LLC 2015-03-12 US disclosed
US-8916065-B2 Phosphite compositions ADDIVANT SWITZERLAND GMBH (CH) 2014-12-23 US disclosed
US-20140045981-A1 PHOSPHITE COMPOSITIONS SI GROUP, INC. 2014-02-13 US disclosed
WO-2014020170-A1 PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2014-02-06 WO disclosed
EP-1910455-B1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES BASF SE (DE) 2012-08-08 EP disclosed
US-7468410-B2 Adding tris-(sec-butylphenyl)phosphite to polyolefin (low density polyethylene) for stabilizing against the deleterious effects of melt processing, heat aging and exposure to combustion products-of natural gas CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-12-23 US disclosed
EP-1910455-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES Ciba Specialty Chemicals Holding Inc. (CH) 2008-04-16 EP disclosed
WO-2007009916-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-25 WO disclosed
US-20070021537-A1 Stabilization of polyolefins with liquid tris-(mono-alkyl)phenyl phosphites CIBA SPECIALTY CHEMICALS CORP. 2007-01-25 US disclosed