SCHEMBL561228

SCHEMBL561228

CCC(C)c1ccccc1OP(Oc1ccccc1C(C)CC)Oc1ccccc1C(C)CC

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.46
NISCH Q9Y2I1 1/20 0.46
HTT P42858 1/20 0.44
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12362394 0.90 L3MBTL1 (0.46) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL10415190 0.90 TSHR (0.46) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL13160836 0.90 TSHR (0.46) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL1649114 0.85 HTT (0.50) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL1649470 0.85 HTT (0.50) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL13160826 0.85 HTT (0.50) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL13160820 0.85 HTT (0.50) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL13160811 0.85 TSHR (0.48) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL4865575 0.85 TSHR (0.53) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL10415188 0.85 TSHR (0.48) TSHRKDM4EL3MBTL1ATMNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10934423-B2 Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers BASF SE (DE) 2021-03-02 US claimed
EP-3649139-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND ORGANOPHOSPHORUS STABILIZERS BASF SE (DE) 2020-05-13 EP claimed
CN-111051322-A Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers 巴斯夫欧洲公司 2020-04-21 CN claimed
WO-2019010166-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND ORGANOPHOSPHORUS STABILIZERS BASF SE (DE) 2019-01-10 WO claimed
US-20190010307-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Organophosphorus Stabilizers BASF CORPORATION 2019-01-10 US claimed
US-8258214-B2 Polymers with low gel content and enhanced gas-fading CHEMTURA CORPORATION (US) 2012-09-04 US claimed
US-20120035305-A1 Polymers with Low Gel Content and Enhanced Gas-Fading SI GROUP, INC. 2012-02-09 US claimed
EP-0263259-B1 PROCESS AND CATALYST SYSTEM FOR THE TRIMERIZATION OF ACETYLENE AND ACETYLENE COMPOUNDS HÜLS AKTIENGESELLSCHAFT (DE) 1991-06-19 EP claimed
US-11623979-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered amine light stabilizers BASF SE (DE) 2023-04-11 US disclosed
US-20220259405-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Amine Light Stabilizers BASF CORPORATION 2022-08-18 US disclosed
US-20220145053-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Phenolic Antioxidants BASF SE (DE) 2022-05-12 US disclosed
US-20220145053-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Phenolic Antioxidants BASF SE (DE) 2022-05-12 US disclosed
US-11274197-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered phenolic antioxidants BASF SE (DE) 2022-03-15 US disclosed
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers BASF SE (DE) 2021-03-09 US disclosed
WO-2007009916-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-25 WO disclosed
WO-2007009916-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-25 WO disclosed
US-20070021537-A1 Stabilization of polyolefins with liquid tris-(mono-alkyl)phenyl phosphites CIBA SPECIALTY CHEMICALS CORP. 2007-01-25 US disclosed
US-20070021537-A1 Stabilization of polyolefins with liquid tris-(mono-alkyl)phenyl phosphites CIBA SPECIALTY CHEMICALS CORP. 2007-01-25 US disclosed
WO-2006130405-A2 PROCESS FOR THE PREPARATION OF POLYISOCYANATES OF THE DIPHENYLMETHANE SERIES HUNTSMAN INTERNATIONAL LLC (US) 2006-12-07 WO disclosed
US-6576788-B1 METHOD FOR PRODUCING MIXTURES CONSISTING OF DIPHENYLMETHANE DIISOCYANATES AND POLYPHENYLENE-POLYMETHYLENE-POLYISOCYANATES CONTAINING A REDUCED AMOUNT OF CHLORINATED SECONDARY PRODUCTS AND WITH A REDUCED IODINE COLOR INDEX BASF AKTIENGESELLSCHAFT (DE) 2003-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190010307-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Organophosphorus Stabilizers PUF60, MORF4L1, BRPF1 TSHR 4031/4885KDM4E 2257/4885L3MBTL1 210/4885
US-11274197-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered phenolic antioxidants PUF60, GPX4, BPTF TSHR 4853/4885KDM4E 2111/4885L3MBTL1 679/4885
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers PUF60, PCBP1, MORF4L1 TSHR 4778/4885KDM4E 3521/4885L3MBTL1 1195/4885
US-10934423-B2 Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers PUF60, MORF4L1, BRPF1 TSHR 4031/4885KDM4E 2257/4885L3MBTL1 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.