Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867630 | 0.88 | ALOX15 (0.40) | ALOX15ALDH1A1TSHRTDP1 | |
| SCHEMBL3899877 | 0.83 | ALOX15 (0.41) | ALOX15ALDH1A1TSHRTDP1 | |
| SCHEMBL20822187 | 0.79 | OPRM1 (0.39) | TSHROPRM1SPHK1CA1 | |
| SCHEMBL237275 | 0.75 | ALOX15 (0.47) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL3108390 | 0.73 | ALOX15 (0.61) | ALOX15ALDH1A1TSHROPRM1USP2 | |
| SCHEMBL3125002 | 0.73 | ALOX15 (0.61) | ALOX15ALDH1A1TSHROPRM1USP2 | |
| SCHEMBL3108399 | 0.73 | ALOX15 (0.61) | ALOX15ALDH1A1TSHROPRM1USP2 | |
| SCHEMBL1532213 | 0.73 | FNTA (0.45) | ALOX15ALDH1A1 | |
| SCHEMBL13129918 | 0.73 | TSHR (0.39) | TSHROPRM1 | |
| SCHEMBL10987090 | 0.72 | TSHR (0.46) | TSHROPRM1SPHK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361630-B2 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANIES INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361630-B2 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANIES INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361630-B2 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANIES INC. (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1762565-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1762565-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-03-14 | — | — | EP | disclosed |
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | ARNT, HCCS, AHR | ALOX15 1051/4885ALDH1A1 2282/4885TSHR 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.