Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870345 | 0.90 | EGLN1 (0.36) | EGLN1GRIA2MEN1KMT2AS1PR3 | |
| SCHEMBL7369650 | 0.73 | EGLN1 (0.44) | EGLN1GRIA2MEN1KMT2AALDH1A1 | |
| SCHEMBL4860980 | 0.71 | MEN1 (0.33) | MEN1KMT2AS1PR3 | |
| SCHEMBL10709923 | 0.69 | MEN1 (0.65) | MEN1KMT2AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7367667 | 0.67 | KDM4E (0.45) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL10623462 | 0.61 | ALDH1A1 (0.44) | MEN1KMT2AS1PR3ALDH1A1MAPT | |
| SCHEMBL8409149 | 0.61 | — | — | |
| SCHEMBL8409152 | 0.61 | — | — | |
| SCHEMBL190463 | 0.60 | — | — | |
| SCHEMBL7422071 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102509-A | Difluoromethylthioether compound, and preparation method and application thereof | 浙江工业大学 | 2023-05-12 | — | — | CN | claimed |
| CN-114539107-A | Aromatic sulfonyl modified difluoromethyl reaction building block and synthesis method thereof | 平顶山学院 | 2022-05-27 | — | — | CN | claimed |
| US-20150336866-A1 | SYNTHESIS OF DIFLUOROMETHYL ETHERS AND SULFIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-11-26 | — | — | US | claimed |
| WO-2014107380-A1 | SYNTHESIS OF DIFLUOROMETHYL ETHERS AND SULFIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-10 | — | — | WO | claimed |
| JP-2007516172-A | — | — | 2007-06-21 | — | — | JP | claimed |
| US-7199106-B2 | Lincomycin derivatives possessing antimicrobial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | claimed |
| EP-1644393-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2006-04-12 | — | — | EP | claimed |
| US-20050043248-A1 | Novel lincomycin derivatives possessing antimicrobial activity | VICURON PHARMACEUTICALS INC. | 2005-02-24 | — | — | US | claimed |
| WO-2005012320-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | claimed |
| CN-120208831-A | Synthesis method of difluoro methyl sulfonyl imide alkali metal salt | 华中科技大学 | 2025-06-27 | — | — | CN | disclosed |
| CN-116003312-B | Method for preparing meta-trifluoromethyl thio, difluoromethylthio or trifluoromethyl substituted pyridine compound | 南开大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-111117594-B | Electrochromic material and electrochromic device based on dynamic metal-ligand complexation | 吉林大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116102509-A | Difluoromethylthioether compound, and preparation method and application thereof | 浙江工业大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-109643822-B | Nonaqueous electrolyte composition comprising fluorinated sulfone | 索尔维公司 | 2023-04-28 | — | — | CN | disclosed |
| US-20060148722-A1 | Novel lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-07-06 | — | — | US | disclosed |
| WO-2006055070-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| EP-1644393-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050215488-A1 | Such as 5-propyl-azepane-2-carboxylic acid [2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydro-pyran-2-yl)-propyl]-amide; for prevention and treatment of mycobacterial, mycoplasmal or chlamydia infection; microbiocides | VICURON PHARMACEUTICALS INC. | 2005-09-29 | — | — | US | disclosed |
| US-20050043248-A1 | Novel lincomycin derivatives possessing antimicrobial activity | VICURON PHARMACEUTICALS INC. | 2005-02-24 | — | — | US | disclosed |
| WO-2005012320-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336866-A1 | SYNTHESIS OF DIFLUOROMETHYL ETHERS AND SULFIDES | DDT, ABL1, TYR | EGLN1 959/4885GRIA2 3291/4885MEN1 4119/4885 |
| US-20060148722-A1 | Novel lincomycin derivatives possessing antibacterial activity | LCLAT1, LAS1L, NRDC | EGLN1 2954/4885GRIA2 4596/4885MEN1 4303/4885 |
| US-20050215488-A1 | Such as 5-propyl-azepane-2-carboxylic acid [2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydro-pyran-2-yl)-propyl]-amide; for prevention and treatment of mycobacterial, mycoplasmal or chlamydia infection; microbiocides | PAM, MLYCD, PPT1 | EGLN1 2235/4885GRIA2 4280/4885MEN1 3653/4885 |
| US-20050043248-A1 | Novel lincomycin derivatives possessing antimicrobial activity | LCLAT1, NRDC, LAS1L | EGLN1 3101/4885GRIA2 4661/4885MEN1 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.