SCHEMBL486819

SCHEMBL486819

C=C(C)C(=O)NS(=O)(=O)C(C)CC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.39
TSHR P16473 1/20 0.34
RXFP1 Q9HBX9 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27565047 0.74 TGFBR1 (0.37) TGFBR1TSHRRXFP1ALDH1A1
SCHEMBL5508115 0.73 TSHR (0.42) TSHRALDH1A1
SCHEMBL195115 0.73 TGFBR1 (0.41) TGFBR1ALDH1A1
SCHEMBL8095059 0.72 CA2 (0.33) TSHR
SCHEMBL6490221 0.71 GRIA1 (0.33)
SCHEMBL349465 0.71 TGFBR1 (0.40) TGFBR1TSHRRXFP1ALDH1A1
SCHEMBL27565040 0.68 TGFBR1 (0.37) TGFBR1TSHRRXFP1ALDH1A1
SCHEMBL21086855 0.68 TGFBR1 (0.37) TGFBR1ALDH1A1
SCHEMBL27998242 0.68 TSHR (0.46) TGFBR1TSHRRXFP1ALDH1A1
SCHEMBL605594 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2411346-A1 WATER-REDUCING AGENT FOR HYDRAULIC BINDERS Lafarge Gypsum International (FR) 2012-02-01 EP disclosed
US-20110262738-A1 Aqueous Organic-Inorganic Hybrid Composition NIGUMA TATSURO 2011-10-27 US disclosed
US-8013055-B2 Aqueous organic-inorganic hybrid composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-09-06 US disclosed
US-20090286068-A1 AQUEOUS ORGANIC-INORGANIC HYBRID COMPOSITION ASAHI KASEI E-MATERIALS CORPORATION (JP) 2009-11-19 US disclosed