SCHEMBL195115

SCHEMBL195115

C=C(C)C(=O)NS(=O)(=O)CC

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.41
HPGD P15428 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21086855 0.85 TGFBR1 (0.37) TGFBR1ALDH1A1
SCHEMBL5190851 0.79 TGFBR1 (0.36) TGFBR1
SCHEMBL349465 0.79 TGFBR1 (0.40) TGFBR1ALDH1A1TDP1
SCHEMBL23732952 0.77
SCHEMBL4603325 0.77 TGFBR1 (0.35) TGFBR1
SCHEMBL194405 0.75 TGFBR1 (0.39) TGFBR1ALDH1A1TDP1KDM4E
SCHEMBL463470 0.75 TGFBR1 (0.39) TGFBR1ALDH1A1TDP1KDM4E
SCHEMBL13253141 0.75 KDM5B (0.36) HPGD
SCHEMBL19313438 0.74
SCHEMBL4719324 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365515-B2 Oxime ester photoinitiators BASF SE (DE) 2016-06-14 US disclosed
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2014-11-13 US disclosed
US-8524425-B2 Oxime ester photoinitiators BASF SE (DE) 2013-09-03 US disclosed
US-8349548-B2 Oxime ester photoinitiators BASF SE (DE) 2013-01-08 US disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 US disclosed
EP-2285836-B1 PHOTOINITIATOR MIXTURES BASF SE (DE) 2012-01-18 EP disclosed
EP-2402315-A1 Oxime ester photoinitiators BASF SE (DE) 2012-01-04 EP disclosed
EP-1410109-B1 PHOTOSENSITIVE RESIN COMPOSITION BASF SE (DE) 2011-10-26 EP disclosed
US-20110218266-A1 PHOTOINITIATOR MIXTURES BASF SE (DE) 2011-09-08 US disclosed
US-20110170209-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2011-07-14 US disclosed
US-7648738-B2 for photopolymerization; photography, relief imaging; color filters CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-19 US disclosed
US-20090293769-A1 BLUE PHTHALOCYANINE PIGMENT COMPOSITION AND ITS PREPARATION CIBA CORPORATION (US) 2009-12-03 US disclosed
US-7556843-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-07-07 US disclosed
US-7425585-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-16 US disclosed
US-20080206658-A1 Compositions Containing Anthraquinone Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-08-28 US disclosed
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-04-24 US disclosed
US-20070259278-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-11-08 US disclosed
US-20070249748-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-10-25 US disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
US-5571642-A LIGHT SENSITIVE ELEMENTS WITH CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1996-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes ZKSCAN2, INCENP, CRY2 TGFBR1 2026/4885HPGD 3325/4885ALDH1A1 1669/4885
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS CBR3, OR10J3, CHRM1 TGFBR1 2429/4885HPGD 872/4885ALDH1A1 1994/4885
US-20110170209-A1 OXIME ESTER PHOTOINITIATORS RAD51, CBR3, CBR1 TGFBR1 2067/4885HPGD 1119/4885ALDH1A1 445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.