SCHEMBL349465

SCHEMBL349465

C=C(C)C(=O)NS(=O)(=O)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.40
TSHR P16473 1/20 0.35
RXFP1 Q9HBX9 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195115 0.79 TGFBR1 (0.41) TGFBR1ALDH1A1TDP1
SCHEMBL13155208 0.79 ALDH1A1 (0.35) TSHRALDH1A1TDP1
SCHEMBL4603325 0.74 TGFBR1 (0.35) TGFBR1
SCHEMBL21086855 0.73 TGFBR1 (0.37) TGFBR1ALDH1A1
SCHEMBL27998242 0.73 TSHR (0.46) TGFBR1TSHRRXFP1ALDH1A1
SCHEMBL8909752 0.72 ALDH1A1 (0.39) ALDH1A1
SCHEMBL3279249 0.72 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL5190851 0.72 TGFBR1 (0.36) TGFBR1
SCHEMBL9637961 0.72 TGFBR1 (0.37) TGFBR1TSHRRXFP1ALDH1A1
SCHEMBL486819 0.71 TGFBR1 (0.39) TGFBR1TSHRRXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016059-A1 WATER-REDUCING AGENT FOR HYDRAULIC BINDERS LAFARGE GYPSUM INTERNATIONAL (FR) 2012-01-19 US claimed
US-10208203-B2 Monomer composition containing unsaturated polyalkylene glycol ether-based monomer, method for producing composition thereof, polymer obtained using composition thereof, and method for producing polymer thereof NIPPON SHOKUBAI CO., LTD. (JP) 2019-02-19 US disclosed
US-20180086912-A1 MONOMER COMPOSITION CONTAINING UNSATURATED POLYALKYLENE GLYCOL ETHER-BASED MONOMER, METHOD FOR PRODUCING COMPOSITION THEREOF, POLYMER OBTAINED USING COMPOSITION THEREOF, AND METHOD FOR PRODUCING POLYMER THEREOF NIPPON CATALYTIC CHEM IND (JP) 2018-03-29 US disclosed
US-9850378-B2 Monomer composition containing unsaturated polyalkylene glycol ether-based monomer, method for producing composition thereof, polymer obtained using composition thereof, and method for producing polymer thereof NIPPON SHOKUBAI CO., LTD. (JP) 2017-12-26 US disclosed
EP-2623528-B1 MONOMER COMPOSITION CONTAINING UNSATURATED POLYALKYLENE GLYCOL ETHER-BASED MONOMER, METHOD FOR PRODUCING COMPOSITION, POLYMER OBTAINED USING COMPOSITION, AND METHOD FOR PRODUCING POLYMER NIPPON CATALYTIC CHEM IND (JP) 2017-11-29 EP disclosed
EP-2079670-B1 AQUEOUS DISPERSIONS OF PRECIPITATED SILICA FOR INCREASING EARLY STRENGTH IN CEMENTITIOUS PREPARATIONS EVONIK DEGUSSA GMBH (DE) 2016-08-03 EP disclosed
EP-1767555-B1 Novel polymer and cement admixture using the same NIPPON CATALYTIC CHEM IND (JP) 2016-06-29 EP disclosed
EP-2623528-A1 MONOMER COMPOSITION CONTAINING UNSATURATED POLYALKYLENE GLYCOL ETHER-BASED MONOMER, METHOD FOR PRODUCING COMPOSITION, POLYMER OBTAINED USING COMPOSITION, AND METHOD FOR PRODUCING POLYMER Nippon Shokubai Co., Ltd. (JP) 2013-08-07 EP disclosed
US-20130184420-A1 MONOMER COMPOSITION CONTAINING UNSATURATED POLYALKYLENE GLYCOL ETHER-BASED MONOMER, METHOD FOR PRODUCING COMPOSITION THEREOF, POLYMER OBTAINED USING COMPOSITION THEREOF, AND METHOD FOR PRODUCING POLYMER THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 2013-07-18 US disclosed
US-8344085-B2 Polymer and cement admixture using the same NIPPON SHOKUBAI CO., LTD. (JP) 2013-01-01 US disclosed
US-8058328-B2 Polycarboxylic acid-based polymer with lower molecular weight side area ratio P of 50 to 87%: copolymerization product of an acrylic acid and an acrylated polyoxyalkylene glycol; enhances water reduction; flowability; slump retention; workability NIPPON SHOKUBAI CO., LTD. (JP) 2011-11-15 US disclosed
EP-0884290-B2 Process for producing a polycarboxylic acid NIPPON CATALYTIC CHEM IND (JP) 2011-11-09 EP disclosed
EP-1524314-B2 Use as detergent builder and detergent composition NIPPON CATALYTIC CHEM IND (JP) 2011-08-31 EP disclosed
EP-2308807-A1 SHRINKAGE-REDUCING AGENT FOR HYDRAULIC MATERIAL AND SHRINKAGE REDUCING AGENT COMPOSITION FOR HYDRAULIC MATERIAL Nippon Shokubai Co., Ltd. (JP) 2011-04-13 EP disclosed
US-20110065847-A1 METHOD FOR PRODUCING POLYCARBOXYLIC ACID COPOLYMER AND COPOLYMER COMPOSITION FOR CEMENT ADMIXTURE NIPPON SHOKUBAI CO., LTD. (JP) 2011-03-17 US disclosed
US-20110046269-A1 NOVEL POLYMER AND CEMENT ADMIXTURE USING THE SAME YUASA TSUTOMU 2011-02-24 US disclosed
US-7851576-B2 Polymer and cement admixture using the same NIPPON SHOKUBAI CO., LTD. (JP) 2010-12-14 US disclosed
US-20070073022-A1 Novel polymer and cement admixture using the same NIPPON SHOKUBAI CO., LTD. (JP) 2007-03-29 US disclosed
EP-1767555-A2 Novel polymer and cement admixture using the same Nippon Shokubai Co., Ltd. (JP) 2007-03-28 EP disclosed
US-20060223914-A1 Polycarboxylic acid polymer for blending in cement NIPPON SHOKUBAI CO., LTD. (JP) 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208203-B2 Monomer composition containing unsaturated polyalkylene glycol ether-based monomer, method for producing composition thereof, polymer obtained using composition thereof, and method for producing polymer thereof ALOX12, ALOX15, ALOX15B TGFBR1 1129/4885TSHR 3004/4885RXFP1 207/4885
US-20180086912-A1 MONOMER COMPOSITION CONTAINING UNSATURATED POLYALKYLENE GLYCOL ETHER-BASED MONOMER, METHOD FOR PRODUCING COMPOSITION THEREOF, POLYMER OBTAINED USING COMPOSITION THEREOF, AND METHOD FOR PRODUCING POLYMER THEREOF ALOX12, ALOX15, ALOX15B TGFBR1 1129/4885TSHR 3004/4885RXFP1 207/4885
US-20130184420-A1 MONOMER COMPOSITION CONTAINING UNSATURATED POLYALKYLENE GLYCOL ETHER-BASED MONOMER, METHOD FOR PRODUCING COMPOSITION THEREOF, POLYMER OBTAINED USING COMPOSITION THEREOF, AND METHOD FOR PRODUCING POLYMER THEREOF ALOX12, ALOX15, ALOX15B TGFBR1 1063/4885TSHR 3399/4885RXFP1 259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.