SCHEMBL4868262

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4857759	0.83	PTGS2 (0.44)	PTGS2PTGS1TGFBR1KDRMAP4K2
	SCHEMBL4866974	0.81	TGFBR1 (0.38)	TGFBR1ADORA2AADORA1
	SCHEMBL4866956	0.81	TGFBR1 (0.38)	TGFBR1ADORA2AADORA1
	SCHEMBL4865060	0.81	TGFBR1 (0.54)	PTGS2PTGS1TGFBR1
	SCHEMBL4866897	0.80	PTGS2 (0.39)	PTGS2PTGS1TGFBR1IDO1ADORA2A
	SCHEMBL23389951	0.76	TGFBR1 (0.38)	PTGS2PTGS1TGFBR1CSF1RRET
	SCHEMBL29796383	0.76	TGFBR1 (0.38)	PTGS2PTGS1TGFBR1CSF1RRET
	SCHEMBL3092632	0.74	PTGS2 (0.42)	PTGS2PTGS1TGFBR1KDRMAP4K2
	SCHEMBL4868431	0.73	TGFBR1 (0.57)	PTGS2PTGS1TGFBR1MAP4K4ERBB4
	SCHEMBL4865015	0.72	TGFBR1 (0.57)	PTGS2PTGS1TGFBR1FLT1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.