SCHEMBL4879240

SCHEMBL4879240

CCN(CC)C1CCN(C(=O)Cn2c(-c3ccc4nc(-c5ccc(OC)cc5)ccc4c3)c(-c3ccccc3)c3sc(C(=O)O)cc32)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CBX7 O95931 2/20 0.38
CDYL2 Q8N8U2 2/20 0.38
CDYL Q9Y232 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
PIK3CA P42336 2/20 0.37
MTOR P42345 2/20 0.37
ACP1 P24666 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4878773 0.93 CBX7 (0.39) ALDH1A1KDM4ENPSR1MAPK1CBX7
SCHEMBL4868402 0.92 CBX7 (0.42) ALDH1A1KDM4EMAPTHPGDNPSR1
SCHEMBL4866875 0.91 ALDH1A1 (0.39) TDP1ALDH1A1KDM4EMAPTHPGD
SCHEMBL4865010 0.90 TDP1 (0.36) TDP1ALDH1A1KDM4EMAPTHPGD
SCHEMBL4868467 0.90 KDM4E (0.44) TDP1ALDH1A1KDM4EMAPTHPGD
SCHEMBL4879229 0.89 KMT2A (0.36) TDP1ALDH1A1KDM4EMAPTHPGD
SCHEMBL4874071 0.89 ALDH1A1 (0.46) TDP1ALDH1A1KDM4EMAPTHPGD
SCHEMBL4874557 0.88 CBX7 (0.38) CBX7CDYL2CDYLPIK3CAMTOR
SCHEMBL4883873 0.87 CBX7 (0.38) ALDH1A1MAPTNPSR1KMT2ACBX7
SCHEMBL4867721 0.87 CBX7 (0.38) KDM4ECBX7CDYL2CDYLPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080051384-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. 2008-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051384-A1 ANTIVIRAL AGENTS EIF2AK2, MAVS, ZC3HAV1 TDP1 1009/4885ALDH1A1 1357/4885KDM4E 3075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.