Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867742 | 1.00 | HCAR3 (0.55) | HCAR3ALDH1A1RECQLGAAMAPT | |
| SCHEMBL4869513 | 1.00 | HCAR3 (0.55) | HCAR3ALDH1A1RECQLGAAMAPT | |
| SCHEMBL4868077 | 0.89 | ALDH1A1 (0.47) | HCAR3ALDH1A1RECQLGAAMAPT | |
| SCHEMBL4863985 | 0.89 | ALDH1A1 (0.47) | HCAR3ALDH1A1RECQLGAAMAPT | |
| SCHEMBL8742128 | 0.86 | CRHBP (0.56) | HCAR3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL4301791 | 0.86 | CRHBP (0.56) | HCAR3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL4869095 | 0.85 | HCAR3 (0.54) | HCAR3ALDH1A1RECQLGAAMAPT | |
| SCHEMBL14764687 | 0.83 | MEN1 (0.57) | HCAR3ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL28745633 | 0.83 | MAPT (0.70) | HCAR3ALDH1A1GAAMAPTKCNMA1 | |
| SCHEMBL28062163 | 0.82 | KMT2A (0.53) | HCAR3ALDH1A1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351709-B2 | Estrogen receptor ligands | WYETH (US) | 2008-04-01 | — | — | US | disclosed |
| US-20060019961-A1 | Estrogen receptor ligands | WYETH | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019961-A1 | Estrogen receptor ligands | GPER1, ESR2, ESR1 | HCAR3 57/4885ALDH1A1 1051/4885RECQL 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.