Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 9/20 | 0.80 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.80 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.80 |
| ▸ | HTR1A | P08908 | 2/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.80 |
| ▸ | DRD2 | P14416 | 2/20 | 0.80 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.80 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.80 |
| ▸ | HTR2A | P28223 | 2/20 | 0.80 |
| ▸ | DRD3 | P35462 | 2/20 | 0.80 |
| ▸ | HTR2B | P41595 | 2/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.80 |
| ▸ | HTR7 | P34969 | 1/20 | 0.80 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.80 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4879538 | 0.99 | ADRA1A (0.78) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL9124000 | 0.91 | ADRA1A (0.75) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL14270986 | 0.90 | ADRA1A (0.77) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL13697643 | 0.90 | ADRA1A (0.77) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL12453523 | 0.90 | ADRA1A (0.80) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29599595 | 0.89 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL34378 | 0.89 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL30361066 | 0.89 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL53998 | 0.89 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29566149 | 0.89 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167317-A1 | Combination Therapy | RANBAXY LABORATORIES LIMITED (IN) | 2008-07-10 | — | — | US | claimed |
| WO-2005092342-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-06 | — | — | WO | claimed |
| US-20050154231-A1 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-14 | — | — | US | claimed |
| US-6894188-B1 | Tamsulosin derivative | RANBAXY LABORATORY LIMITED (IN) | 2005-05-17 | — | — | US | claimed |
| EP-1501793-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES, LTD. (IN) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093227-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES LIMITED (IN) | 2003-11-13 | — | — | WO | claimed |
| US-20080167317-A1 | Combination Therapy | RANBAXY LABORATORIES LIMITED (IN) | 2008-07-10 | — | — | US | disclosed |
| US-7084301-B2 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-01 | — | — | US | disclosed |
| US-7084301-B2 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-01 | — | — | US | disclosed |
| WO-2005092342-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-06 | — | — | WO | disclosed |
| US-20050154231-A1 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-14 | — | — | US | disclosed |
| US-20050154231-A1 | Tamsulosin derivative | RANBAXY LABORATORIES LIMITED (IN) | 2005-07-14 | — | — | US | disclosed |
| US-6894188-B1 | Tamsulosin derivative | RANBAXY LABORATORY LIMITED (IN) | 2005-05-17 | — | — | US | disclosed |
| US-6894188-B1 | Tamsulosin derivative | RANBAXY LABORATORY LIMITED (IN) | 2005-05-17 | — | — | US | disclosed |
| EP-1501793-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES, LTD. (IN) | 2005-02-02 | — | — | EP | disclosed |
| EP-1501793-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES, LTD. (IN) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093227-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES LIMITED (IN) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003093227-A1 | TAMSULOSIN DERIVATIVE | RANBAXY LABORATORIES LIMITED (IN) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154231-A1 | Tamsulosin derivative | ADRB1, ADRA1B, ADRA2B | ADRA1A 7/4885ADRA1D 5/4885ADRA1B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.