SCHEMBL487003

SCHEMBL487003

CNC(C)CCCc1ccc(CCCC(C)NC)cc1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.43
TAAR1 Q96RJ0 2/20 0.43
SLC18A2 Q05940 1/20 0.43
SLC6A4 P31645 2/20 0.42
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23875151 0.90 SIGMAR1 (0.50) SIGMAR1SLC6A4HTT
SCHEMBL9628206 0.90 SIGMAR1 (0.50) SIGMAR1SLC6A4HTT
SCHEMBL15907606 0.90 SIGMAR1 (0.59) SIGMAR1TAAR1SLC18A2
SCHEMBL9627281 0.87 HTT (0.57) SIGMAR1TAAR1HTTSMN1; SMN2
SCHEMBL20019912 0.79 TAAR1 (0.34) SIGMAR1TAAR1SLC18A2SLC6A4
SCHEMBL487002 0.78 TAAR1 (0.45) SIGMAR1TAAR1SLC18A2SLC6A4HTT
SCHEMBL21779818 0.78 ALDH1A1 (0.49) SIGMAR1TAAR1SLC18A2SLC6A4HTT
SCHEMBL18182128 0.77 OPRK1 (0.60) SIGMAR1SLC6A4HTT
SCHEMBL4958679 0.77 TDP1 (0.56)
SCHEMBL178505 0.76 TAAR1 (0.63) SIGMAR1TAAR1SLC18A2HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11401381-B2 Modified silicone compound, and thermosetting resin composition, prepreg, laminate plate and printed wiring board using same SHOWA DENKO MATERIALS CO., LTD. (JP) 2022-08-02 US disclosed
EP-2412743-B1 THERMOSETTING RESIN COMPOSITION, AND PREPREG, INSULATING FILM WITH SUPPORT, LAMINATE PLATE, AND PRINTED WIRING BOARD, EACH OBTAINED USING SAME HITACHI CHEMICAL CO LTD (JP) 2020-08-19 EP disclosed
US-10119047-B2 Thermosetting resin composition, and prepreg, insulating film with support, laminate plate, and printed wiring board, each obtained using same HITACHI CHEMICAL COMPANY, LTD. (JP) 2018-11-06 US disclosed
US-20150203715-A1 Thermosetting Resin Composition, and Prepreg, Insulating Film With Support, Laminate Plate, and Printed Wiring Board, Each Obtained Using Same RESONAC CORPORATION (JP) 2015-07-23 US disclosed
US-20130330563-A1 MODIFIED SILICONE COMPOUND, AND THERMOSETTING RESIN COMPOSITION, PREPREG, LAMINATE PLATE AND PRINTED WIRING BOARD USING SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-12-12 US disclosed
EP-2666804-A1 MODIFIED SILICONE COMPOUND, AND THERMOSETTING RESIN COMPOSITION, PREPREG, LAMINATE PLATE AND PRINTED WIRING BOARD USING SAME Hitachi Chemical Co., Ltd. (JP) 2013-11-27 EP disclosed
US-20120077401-A1 RESIN COMPOSITION FOR PRODUCTION OF CLAD LAYER, RESIN FILM FOR PRODUCTION OF CLAD LAYER UTILIZING THE RESIN COMPOSITION, AND OPTICAL WAVEGUIDE AND OPTICAL MODULE EACH UTILIZING THE RESIN COMPOSITION OR THE RESIN FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-03-29 US disclosed
EP-2412743-A1 THERMOSETTING RESIN COMPOSITION, AND PREPREG, INSULATING FILM WITH SUPPORT, LAMINATE PLATE, AND PRINTED WIRING BOARD, EACH OBTAINED USING SAME Hitachi Chemical Company, Ltd. (JP) 2012-02-01 EP disclosed