Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295575 | 0.98 | LMNA (0.37) | CTSKOPRM1LMNAADH1BADH1C | |
| SCHEMBL8379541 | 0.88 | LMNA (0.39) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL8378685 | 0.88 | LMNA (0.39) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL5949233 | 0.84 | LMNA (0.37) | CTSKOPRM1LMNAADH1BADH1C | |
| SCHEMBL3317322 | 0.83 | — | — | |
| SCHEMBL276891 | 0.80 | CTSK (0.42) | CTSKOPRM1ADH1BADH1CADH1A | |
| SCHEMBL29655326 | 0.80 | CTSK (0.42) | CTSKOPRM1ADH1BADH1CADH1A | |
| SCHEMBL4117542 | 0.80 | CTSK (0.35) | CTSKOPRM1LMNAADH1BADH1C | |
| SCHEMBL195057 | 0.80 | CTSK (0.35) | CTSKOPRM1LMNAADH1BADH1C | |
| SCHEMBL76606 | 0.78 | ADH1B (0.42) | CTSKOPRM1LMNAADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378551-B2 | Amide compound | KAO CORPORATION (JP) | 2008-05-27 | — | — | US | disclosed |
| US-20070185208-A1 | Amide compound | KAO CORPORATION (JP) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185208-A1 | Amide compound | H1-0, H1-2, H1-4 | CTSK 4748/4885OPRM1 1108/4885LMNA 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.