Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870195 | 0.83 | CDK2 (0.46) | CDK2KCNK3KCNK9RORCRXRA | |
| SCHEMBL29374906 | 0.80 | KDM4E (0.53) | KCNK3KCNK9RXRARXRBRXRG | |
| SCHEMBL219675 | 0.80 | KDM4E (0.53) | KCNK3KCNK9RXRARXRBRXRG | |
| SCHEMBL4865208 | 0.78 | TAS2R14 (0.46) | CDK2KCNK3KCNK9MMP2HTT | |
| SCHEMBL5784212 | 0.78 | ELANE (0.52) | CDK2KCNK3KCNK9RXRARXRB | |
| SCHEMBL161228 | 0.77 | G6PD (0.50) | CDK2KCNK3KCNK9MMP2RXRA | |
| Hydrochloric Acid SCHEMBL3071146 | 0.76 | G6PD (0.49) | CDK2KCNK3KCNK9MMP2RXRA | |
| SCHEMBL27286117 | 0.76 | CDK2 (0.41) | CDK2KCNK3KCNK9RXRARXRB | |
| SCHEMBL10937430 | 0.76 | ELANE (0.57) | CDK2KCNK3KCNK9RXRARXRB | |
| SCHEMBL20641942 | 0.76 | HTT (0.43) | CDK2KCNK3KCNK9HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293790-A1 | SUBSTITUTED ARYL OXIMES | WYETH (US) | 2008-11-27 | — | — | US | disclosed |
| US-7420083-B2 | Substituted aryloximes | WYETH (US) | 2008-09-02 | — | — | US | disclosed |
| US-20050070584-A1 | Substituted aryloximes | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070584-A1 | Substituted aryloximes | AHR, NQO1, AOX1 | CDK2 751/4885KCNK3 3040/4885KCNK9 4566/4885 |
| US-20080293790-A1 | SUBSTITUTED ARYL OXIMES | HCCS, AOX1, TET2 | CDK2 776/4885KCNK3 3300/4885KCNK9 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.