Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487069 | 0.88 | MAPT (0.44) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| SCHEMBL13211382 | 0.87 | MAPT (0.53) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| SCHEMBL5341171 | 0.85 | ALDH1A1 (0.50) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL12273311 | 0.82 | SMN1; SMN2 (0.42) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| SCHEMBL30167007 | 0.79 | HSPB1 (0.53) | KMT2AMAPTPOLBALDH1A1CYP1A2 | |
| SCHEMBL12273892 | 0.78 | NR4A1 (0.42) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| SCHEMBL502729 | 0.77 | ALDH1A1 (0.40) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| SCHEMBL12273312 | 0.77 | AKR1B10 (0.40) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL12273007 | 0.77 | NR4A1 (0.41) | KMT2AMEN1MAPTPOLBL3MBTL1 | |
| SCHEMBL487505 | 0.77 | SMN1; SMN2 (0.40) | KMT2AMEN1MAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816552-B2 | Intermediate of 6-substituted 1-methyl-1-H-benzimidazole derivative and method for producing same | SANKYO COMPANY, LIMITED (JP) | 2010-10-19 | — | — | US | claimed |
| US-20090023929-A1 | Intermediate of 6-Substituted 1-Methyl-1-H-Benzimidazole Derivative and Method for Producing Same | SANKYO COMPANY, LIMITED (JP) | 2009-01-22 | — | — | US | claimed |
| EP-2505587-A1 | METHOD FOR MANUFACTURING A 6-SUBSTITUTED-1-METHYL-1H-BENZIMIDAZOLE DERIVATIVE, AND MANUFACTURING INTERMEDIATE FROM SAID METHOD | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-10-03 | — | — | EP | disclosed |
| US-20120238759-A1 | METHOD FOR MANUFACTURING A 6-SUBSTITUTED 1-METHYL-1H-BENZIMIDAZOLE DERIVATIVE AND AN INTERMEDIATE OF SAID METHOD | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-09-20 | — | — | US | disclosed |
| CN-102391203-A | Intermediate of 6-substituted-1-methyl-1-h-benzimidazole derivative and method for producing same | SANKYO CO | 2012-03-28 | — | — | CN | disclosed |
| US-8106079-B2 | Intermediate of 6-substituted-1-methyl-1-H-benzimidazole derivative and method for producing same | SANKYO COMPANY, LIMITED (JP) | 2012-01-31 | — | — | US | disclosed |
| CN-101068770-B | Process for producing 6-substituted-1-methyl-1-H-benzimidazole derivative and synthetic intermediate therefor | SANKYO CO | 2012-01-04 | — | — | CN | disclosed |
| US-7816552-B2 | Intermediate of 6-substituted 1-methyl-1-H-benzimidazole derivative and method for producing same | SANKYO COMPANY, LIMITED (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20100234612-A1 | Intermediate of 6-substituted-1-methyl-1-H-benzimidazole derivative and method for producing same | SANKYO COMPANY, LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20090023929-A1 | Intermediate of 6-Substituted 1-Methyl-1-H-Benzimidazole Derivative and Method for Producing Same | SANKYO COMPANY, LIMITED (JP) | 2009-01-22 | — | — | US | disclosed |
| CN-101068770-A | Process for producing 6-substituted-1-methyl-1-H-benzimidazole derivative and synthetic intermediate therefor | SANKYO CO (JP) | 2007-11-07 | — | — | CN | disclosed |
| EP-1798216-A1 | INTERMEDIATE OF 6-SUBSTITUTED-1-METHYL-1-H-BENZIMIDAZOLE DERIVATIVE AND METHOD FOR PRODUCING SAME | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023929-A1 | Intermediate of 6-Substituted 1-Methyl-1-H-Benzimidazole Derivative and Method for Producing Same | AZI2, CYC1, CCNI | KMT2A 1359/4885MEN1 2082/4885MAPT 4036/4885 |
| US-20120238759-A1 | METHOD FOR MANUFACTURING A 6-SUBSTITUTED 1-METHYL-1H-BENZIMIDAZOLE DERIVATIVE AND AN INTERMEDIATE OF SAID METHOD | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, IL4I1, H1-4 | KMT2A 398/4885MEN1 335/4885MAPT 3553/4885 |
| US-20100234612-A1 | Intermediate of 6-substituted-1-methyl-1-H-benzimidazole derivative and method for producing same | CYC1, CYP2B6, COX6B1 | KMT2A 625/4885MEN1 1306/4885MAPT 4386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.