SCHEMBL2492329

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4647831	0.84	HDAC4 (0.54)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL4870784	0.80	LMNA (0.39)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL949284	0.78	BACE1 (0.52)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL7005547	0.78	HDAC4 (0.54)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL3976573	0.77	HDAC4 (0.61)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL27749305	0.75	CYP2A6 (0.46)	HDAC4HDAC2HDAC8HDAC6BACE1
	Ethane SCHEMBL27298270	0.75	BACE1 (0.48)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL2489466	0.75	ALOX5AP (0.35)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL5595212	0.75	ALDH1A1 (0.46)	HDAC4HDAC2HDAC8HDAC6BACE1
	SCHEMBL2490178	0.75	BRD4 (0.38)	BACE1ALOX5PDE4BPDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.