SCHEMBL487084

SCHEMBL487084

Cc1ccc(C)c(NC(=O)CN(CC(=O)O)CC(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
BRD4 O60885 1/20 0.56
MAPT P10636 2/20 0.55
HDAC3 O15379 1/20 0.55
HDAC4 P56524 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
HDAC9 Q9UKV0 1/20 0.55
HDAC5 Q9UQL6 1/20 0.55
GAA P10253 1/20 0.53
ALDH1A1 P00352 2/20 0.52
HPGD P15428 1/20 0.52
DRD3 P35462 1/20 0.51
NLRP3 Q96P20 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487184 0.88 MEN1 (0.66) SMN1; SMN2MAPTHDAC3HDAC4HDAC1
SCHEMBL2098801 0.86 MAPT (0.69) POLBSMN1; SMN2BRD4MAPTHDAC3
SCHEMBL30084568 0.86 MAPT (0.69) POLBSMN1; SMN2BRD4MAPTHDAC3
SCHEMBL14188875 0.81 MEN1 (0.60) SMN1; SMN2MAPTHDAC3HDAC4HDAC1
SCHEMBL2009980 0.80 MEN1 (0.72) POLBSMN1; SMN2BRD4HDAC3HDAC4
SCHEMBL14292042 0.80 HDAC3 (0.68) POLBBRD4MAPTHDAC3HDAC4
SCHEMBL17244586 0.77 HDAC3 (0.64) POLBSMN1; SMN2BRD4MAPTHDAC3
SCHEMBL13752250 0.77 HDAC3 (0.64) POLBSMN1; SMN2BRD4HDAC3HDAC4
SCHEMBL486592 0.77 POLB (0.65) POLBSMN1; SMN2MAPTHDAC3HDAC4
SCHEMBL14426831 0.77 GAA (0.78) POLBSMN1; SMN2BRD4HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
CN-104666246-A Orally Bioavailable Lipid-based Constructs SDG INC AN OHIO CORPRATION 2015-06-03 CN claimed
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal SDG, INC. (US) 2011-06-09 US claimed
WO-2011022396-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2011-02-24 WO claimed
US-7871641-B2 Hepatocyte-targeting vehicle for delivery of glargine insulin to a mammal SDG, INC. (US) 2011-01-18 US claimed
US-7858116-B2 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. (US) 2010-12-28 US claimed
CN-101917971-A Orally bioavailable lipid-based structures SDG INC AN OHIO CORP 2010-12-15 CN claimed
EP-2205217-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (an Ohio Corporation ) (US) 2010-07-14 EP claimed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US claimed
WO-2009042945-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (AN OHIO CORPORATION ) (US) 2009-04-02 WO claimed
EP-1883394-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, Inc. (US) 2008-02-06 EP claimed
WO-2006127361-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal SDG, INC. 2006-10-05 US claimed
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. 2006-10-05 US claimed
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US disclosed
EP-1087753-A1 TARGETED LIPOSOMAL DRUG DELIVERY SYSTEM SDG, Inc. (US) 2001-04-04 EP disclosed
WO-1999059545-A1 TARGETED LIPOSOMAL DRUG DELIVERY SYSTEM SDG, INC. (US) 1999-11-25 WO disclosed
EP-0274467-B1 HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM GEHO, W., Blair (US) 1992-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 POLB 4282/4885SMN1; SMN2 3997/4885BRD4 1700/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 POLB 4659/4885SMN1; SMN2 3362/4885BRD4 3129/4885
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL GPR119, INSR, FABP1 POLB 4702/4885SMN1; SMN2 4225/4885BRD4 1380/4885
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal INSR, GPR119, GCG POLB 3957/4885SMN1; SMN2 3866/4885BRD4 3058/4885
US-20090087479-A1 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 POLB 4664/4885SMN1; SMN2 3745/4885BRD4 1406/4885
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal INSR, IAPP, GPR119 POLB 4755/4885SMN1; SMN2 3786/4885BRD4 4537/4885
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal INSR, INSRR, IAPP POLB 4685/4885SMN1; SMN2 3217/4885BRD4 4072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.