Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | FPR1 | P21462 | 2/20 | 0.53 |
| ▸ | FPR2 | P25090 | 2/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871193 | 0.90 | FPR1 (0.49) | POLBLMNAMAPTTHRBFPR1 | |
| SCHEMBL4868688 | 0.89 | LMNA (0.53) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL4867224 | 0.86 | AVPR2 (0.54) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL4870684 | 0.83 | MAPT (0.67) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL6677985 | 0.83 | MAPT (0.51) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL4870223 | 0.81 | TP53 (0.57) | POLBLMNAMAPTTHRBFPR1 | |
| SCHEMBL4867095 | 0.78 | THRB (0.53) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL4866912 | 0.78 | AVPR2 (0.56) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL4870752 | 0.77 | POLB (0.57) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL4868227 | 0.76 | POLB (0.60) | POLBLMNAMAPTTHRBAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368444-B2 | N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-05-06 | — | — | US | claimed |
| EP-1475368-A1 | N-CARBAMOYL NITROGEN-CONTAINING FUSED RING COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-10 | — | — | EP | disclosed |