SCHEMBL487122

SCHEMBL487122

Cc1ccc2sc3cc(C(=O)O)cc(Cl)c3c(=O)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 3/20 0.50
POLB P06746 2/20 0.50
HPGD P15428 2/20 0.50
BCL2L1 Q07817 1/20 0.42
MCL1 Q07820 1/20 0.42
MAPT P10636 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
TTR P02766 6/20 0.39
F10 P00742 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HCRTR1 O43613 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4200676 0.79 ALDH1A1 (0.48) ALDH1A1KDM4EPOLBHPGDBCL2L1
SCHEMBL473687 0.78 BCL2L1 (0.46) ALDH1A1KDM4EPOLBHPGDBCL2L1
Hydrochloric Acid SCHEMBL487123 0.77 ALDH1A1 (0.44) ALDH1A1KDM4EPOLBHPGDBCL2L1
SCHEMBL4536100 0.77 GPR35 (0.39) ALDH1A1BCL2L1MCL1MAPTMEN1
SCHEMBL4542795 0.76 ALDH1A1 (0.49) ALDH1A1KDM4EPOLBHPGDBCL2L1
SCHEMBL28806848 0.75 HPGD (0.36) ALDH1A1KDM4EPOLBHPGDBCL2L1
SCHEMBL11240719 0.73 BCL2L1 (0.49) ALDH1A1KDM4EHPGDBCL2L1MCL1
SCHEMBL1609870 0.73 KDM4E (0.51) ALDH1A1KDM4EPOLBHPGDMAPT
SCHEMBL4537030 0.72 ALDH1A1 (0.51) ALDH1A1KDM4EPOLBHPGDBCL2L1
Acetic Acid SCHEMBL29096278 0.72 KDM4E (0.55) ALDH1A1KDM4EPOLBHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2359943-B1 ULTRA-THIN PHOTO-POLYMERIC COATINGS AND USES THEREOF SURMODICS INC (US) 2014-01-22 EP disclosed
US-8632877-B2 Ultra-thin photo-polymer coatings and uses thereof SURMODICS, INC. (US) 2014-01-21 US disclosed
US-20130052456-A1 ULTRA-THIN PHOTO-POLYMER COATINGS AND USES THEREOF SURMODICS, INC. (US) 2013-02-28 US disclosed
US-8277928-B2 Ultra-thin photo-polymer coatings and uses thereof SURMODICS, INC. (US) 2012-10-02 US disclosed
US-8105666-B2 Compliant polymeric coatings for insertable medical articles BANK OF MONTREAL, AS COLLATERAL AGENT 2012-01-31 US disclosed
EP-2359943-A1 ULTRA-THIN PHOTO-POLYMERIC COATINGS AND USES THEREOF SurModics, Inc. (US) 2011-08-24 EP disclosed
EP-1945380-B1 ULTRA-THIN PHOTO-POLYMERIC COATINGS AND USES THEREOF SURMODICS INC (US) 2011-02-16 EP disclosed
US-20100096320-A1 Ultra-thin photo-polymer coatings and uses thereof SURMODICS, INC. 2010-04-22 US disclosed
US-7547445-B2 Crosslinkable macromers SURMODICS, INC. (US) 2009-06-16 US disclosed
EP-1945380-A2 ULTRA-THIN PHOTO-POLYMERIC COATINGS AND USES THEREOF SurModics, Inc. (US) 2008-07-23 EP disclosed
US-20050136091-A1 Crosslinkable macromers Surmodics Coatings, LLC 2005-06-23 US disclosed
EP-1063975-B1 CROSSLINKABLE MACROMERS BEARING INITIATOR GROUPS SURMODICS INC (US) 2005-05-18 EP disclosed
EP-1395301-A1 CROSSLINKABLE MACROMERS SurModics, Inc. (US) 2004-03-10 EP disclosed
US-20030031697-A1 Crosslinkable macromers Surmodics Coatings, LLC 2003-02-13 US disclosed
WO-2002100453-A1 CROSSLINKABLE MACROMERS SURMODICS, INC. (US) 2002-12-19 WO disclosed
US-6410044-B1 Crosslinkable macromers SURMODICS, INC. 2002-06-25 US disclosed
EP-1063975-A1 CROSSLINKABLE MACROMERS BEARING INITIATOR GROUPS SurModics, Inc. (US) 2001-01-03 EP disclosed
US-6156345-A Crosslinkable macromers bearing initiator groups SURMODICS, INC. (US) 2000-12-05 US disclosed
US-6007833-A RESIN MIXTURE HAVING IMPROVED NONTOXICITY, POLYMERIZATION EFFICIENCY, AND SOLUBILITY WHICH FORMS BIODEGRADABLE MATRIX FOR MEDICAL APPLICATION SURMODICS, INC. (US) 1999-12-28 US disclosed
WO-1999047129-A1 CROSSLINKABLE MACROMERS BEARING INITIATOR GROUPS SURMODICS, INC. (US) 1999-09-23 WO disclosed