Cysteine

Cysteine

SCHEMBL4872171

NC(CS)C(=O)[O-].[K+]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Cysteine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cysteine SCHEMBL4138492 1.00
Cysteine SCHEMBL492744 0.95 PTGS1 (0.56)
Cysteine SCHEMBL16194528 0.94
Cysteine SCHEMBL17473902 0.94
Cysteine SCHEMBL3396204 0.94 PTGS1 (0.55)
Cysteine SCHEMBL23903319 0.94 PTGS1 (0.55)
Cysteine SCHEMBL4864416 0.94 PTGS1 (0.55)
Cysteine SCHEMBL5046068 0.94
Cysteine SCHEMBL5307589 0.94 PTGS1 (0.55)
Cysteine SCHEMBL8501902 0.94 PTGS1 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375246-B2 Sulfhydral containing compounds and methods of using the same REGENESIS BIOREMEDIATION PRODUCTS INC. (US) 2008-05-20 US disclosed
US-20050148712-A1 Polyol esters of sulfhydryl carboxylic acids; treating water and water-containing soils contaminated with metal FARONE WILLIAM A (US) 2005-07-07 US disclosed
US-6846947-B2 Sulfhydral containing compounds and methods of using same REGENESIS BIOREMEDIATION PRODUCTS, INC. (US) 2005-01-25 US disclosed
US-20040157316-A1 Sulfhydral containing compounds and methods of using same REGENESIS 2004-08-12 US disclosed
US-20040158095-A1 Sulfhydral containing compounds and methods of using same REGENESIS, INC. 2004-08-12 US disclosed
US-6733651-B1 Method for producing a cyanide-free solution of a gold compound that is suitable for galvanic gold baths W. C. HERAEUS GMBH & CO. KG (DE) 2004-05-11 US disclosed