SCHEMBL487265

SCHEMBL487265

Cc1cccc(C(=O)P(=O)(c2ccccc2)c2ccccc2)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
AKR1B10 O60218 1/20 0.45
TRPA1 O75762 1/20 0.45
ABCB11 O95342 1/20 0.45
DHFR P00374 1/20 0.45
MPO P05164 1/20 0.45
CYP1A2 P05177 1/20 0.45
CHRM1 P11229 1/20 0.45
AKR1B1 P15121 1/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
AKR1C3 P42330 1/20 0.45
AKR1C2 P52895 1/20 0.45
AKR1C1 Q04828 1/20 0.45
HIF1A Q16665 1/20 0.45
NAPRT Q6XQN6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57823 0.87 HPGD (0.50) LMNAKMT2ACYP3A4CYP2C9HSD17B10
SCHEMBL29984769 0.86 KMT2A (0.38) LMNAKMT2AMEN1CYP3A4CYP2C9
SCHEMBL151071 0.86 KMT2A (0.38) LMNAKMT2AMEN1CYP3A4CYP2C9
SCHEMBL17023658 0.81 CA2 (0.48) KMT2AMEN1NAPRTTDP1HSD17B10
SCHEMBL260684 0.80 HPGD (0.42) LMNAKMT2ATDP1HSD17B10HTT
SCHEMBL25271413 0.78 KMT2A (0.37) LMNAKMT2AMEN1CYP1A2HTT
SCHEMBL18486713 0.77 ALDH1A1 (0.47) LMNAKMT2AMEN1CYP3A4CYP2C9
SCHEMBL988214 0.77 KMT2A (0.39) LMNAKMT2AMEN1CYP1A2HTT
SCHEMBL1186385 0.77 KMT2A (0.41) LMNAKMT2AMEN1CYP1A2HTT
SCHEMBL29634650 0.77 KMT2A (0.41) LMNAKMT2AMEN1CYP1A2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689250-A The coating alloy powder of silver, conductive paste, electronic component and electric device 同和电子科技有限公司 2019-04-26 CN disclosed
CN-104350111-B resin composition for coating material 电化株式会社 2017-10-10 CN disclosed
CN-106963656-A The dentistry machining block composite material of fibre with the different sandwich construction of the transparency 株式会社松风 2017-07-21 CN disclosed
US-8633292-B2 Polyurethane-based photochromic optical materials Signet Armorlite (US) 2014-01-21 US disclosed
EP-2411848-A1 PLYURETHANE-BASED PHOTOCHROMIC OPTICAL MATERIALS Signet Armorlite Inc. (US) 2012-02-01 EP disclosed
WO-2010110917-A1 PLYURETHANE-BASED PHOTOCHROMIC OPTICAL MATERIALS SIGNET ARMORLITE INC. (US) 2010-09-30 WO disclosed
US-20100249264-A1 Polyurethane-based photochromic optical materials SIGNET ARMORLITE, INC. 2010-09-30 US disclosed
EP-1667745-B1 LUBRICIOUS COATING BOSTON SCIENT LTD (BB) 2009-12-16 EP disclosed
US-20070078388-A1 Lubricious coating BOSTON SCIENTIFIC SCIMED, INC. (US) 2007-04-05 US disclosed
EP-1667745-A1 LUBRICIOUS COATING Boston Scientific Limited (BB) 2006-06-14 EP disclosed
WO-2005025631-A1 LUBRICIOUS COATING BOSTON SCIENTIFIC LIMITED (BB) 2005-03-24 WO disclosed
US-20050054774-A1 Lubricious coating SCIMED LIFE SYSTEMS, INC. (US) 2005-03-10 US disclosed