Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249667 | 0.95 | FDFT1 (0.39) | LMNAFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL3253080 | 0.90 | FDFT1 (0.40) | LMNAFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL3251156 | 0.88 | FLT1 (0.42) | LMNAFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL3249174 | 0.85 | L3MBTL1 (0.44) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3248909 | 0.85 | LMNA (0.43) | LMNAFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL3246435 | 0.85 | ALDH1A1 (0.42) | LMNAFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL3251363 | 0.84 | SMN1; SMN2 (0.43) | LMNAFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL3247544 | 0.84 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3246730 | 0.83 | LPAR1 (0.44) | LMNAFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL3244695 | 0.82 | CYP1A2 (0.48) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396958-B2 | Sulphonamide derivatives, their preparation and their therapeutic application | SANOFI AVENTIS (FR) | 2008-07-08 | — | — | US | disclosed |