Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302645 | 0.88 | MAPT (0.50) | MAPTHSD17B10EPHX1TSHRRECQL | |
| SCHEMBL617437 | 0.82 | MAPT (0.43) | MAPTHSD17B10EPHX1TSHRRECQL | |
| SCHEMBL301433 | 0.78 | TSHR (0.51) | HSD17B10TSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2487164 | 0.75 | — | — | |
| SCHEMBL291784 | 0.74 | MMP1 (0.33) | SMN1; SMN2MMP9MMP8 | |
| SCHEMBL14889325 | 0.73 | TSHR (0.47) | HSD17B10TSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL18287161 | 0.73 | EPHX1 (0.59) | EPHX1SMN1; SMN2MMP8 | |
| SCHEMBL18287168 | 0.73 | EPHX1 (0.59) | EPHX1SMN1; SMN2MMP8 | |
| SCHEMBL18287170 | 0.73 | EPHX1 (0.59) | EPHX1SMN1; SMN2MMP8 | |
| SCHEMBL3240918 | 0.72 | MMP8 (0.34) | TSHRSMN1; SMN2ALDH1A1MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |