Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807533 | 0.86 | PIK3CD (0.33) | MMP8PIK3CDCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL12449353 | 0.82 | KDM4C (0.42) | MMP1MMP2MMP3MMP9KMT2A | |
| SCHEMBL18907822 | 0.81 | MMP8 (0.34) | MMP8MMP1MMP2MMP3MMP9 | |
| SCHEMBL2487164 | 0.80 | — | — | |
| SCHEMBL18287163 | 0.79 | PIK3CD (0.32) | PIK3CDCYP2D6CYP2C19 | |
| SCHEMBL18287159 | 0.79 | FAAH (0.34) | FAAHCYP2D6CYP2C19TSHRUSP2 | |
| SCHEMBL291397 | 0.77 | ALDH1A1 (0.41) | KMT2APIK3CDCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18287157 | 0.76 | ANPEP (0.42) | MMP8MMP2KMT2ASMN1; SMN2 | |
| SCHEMBL18287161 | 0.76 | EPHX1 (0.59) | MMP8KMT2AFAAHSMN1; SMN2 | |
| SCHEMBL11339189 | 0.76 | GAA (0.49) | MMP8CYP2C19SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105168009-A | Water-soluble dropping pills containing compound cooling agent and preparation method of dropping pills | ANHUI FENGLE PERFUME CO LTD | 2015-12-23 | — | — | CN | claimed |
| US-4296255-A | USEFUL IN TOILETRIES | WILKINSON SWORD LIMITED (GB) | 1981-10-20 | — | — | US | claimed |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-05-31 | — | — | US | disclosed |
| EP-2844094-B1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS SA (CH) | 2021-01-27 | — | — | EP | disclosed |
| US-20200297607-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2020-09-24 | — | — | US | disclosed |
| EP-3699250-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | Takasago International Corporation (JP) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019078185-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | 高砂香料工業株式会社 | 2019-04-25 | — | — | WO | disclosed |
| US-20180220699-A1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-08-09 | — | — | US | disclosed |
| US-20180220699-A1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-08-09 | — | — | US | disclosed |
| US-9949505-B2 | Smoking article mouthpiece with cooling agent inclusion complex | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-04-24 | — | — | US | disclosed |
| US-9949505-B2 | Smoking article mouthpiece with cooling agent inclusion complex | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-04-24 | — | — | US | disclosed |
| US-20070202212-A1 | CHEWING GUM CONTAINING CONTROLLED RELEASE ACYCLIC CARBOXAMIDES | WM. WRIGLEY JR. COMPANY | 2007-08-30 | — | — | US | disclosed |
| US-20070092553-A1 | Compositions and methods of making rapidly dissolving lonically masked formulations | PFAB LP (US) | 2007-04-26 | — | — | US | disclosed |
| EP-1011643-A4 | CHEWING GUM CONTAINING CONTROLLED RELEASE ACYCLIC CARBOXAMIDES | WRIGLEY W M JUN CO (US) | 2004-10-20 | — | — | EP | disclosed |
| US-20030082271-A1 | Chewing gum containing controlled release acyclic carboxamides | WM. WRIGLEY, JR. COMPANY | 2003-05-01 | — | — | US | disclosed |
| EP-1011643-A1 | CHEWING GUM CONTAINING CONTROLLED RELEASE ACYCLIC CARBOXAMIDES | WM. WRIGLEY JR. COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999013870-A1 | CHEWING GUM CONTAINING CONTROLLED RELEASE ACYCLIC CARBOXAMIDES | WM. WRIGLEY JR. COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |
| US-4296255-A | USEFUL IN TOILETRIES | WILKINSON SWORD LIMITED (GB) | 1981-10-20 | — | — | US | disclosed |
| US-4230688-A | FOODS, TOILETRIES | WILKINSON SWORD LIMITED (GB) | 1980-10-28 | — | — | US | disclosed |
| US-4153679-A | IN TOILETRIES, FOODS, BEVERAGES AND TOBACCO PRODUCTS | WILKINSON SWORD LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200297607-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | CNR2, ADRB2, TRPA1 | MMP8 1384/4885MMP1 920/4885MMP2 4587/4885 |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | CNR2, ADRB2, TRPA1 | MMP8 1384/4885MMP1 920/4885MMP2 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.