Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874296 | 0.82 | ALDH1A1 (0.71) | ALDH1A1SLC6A4SLC6A3KDRHTR1A | |
| SCHEMBL22811884 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SLC6A9CYP3A4MAPTROCK2 | |
| SCHEMBL14085833 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SLC6A4SLC6A3KDRCYP3A4 | |
| SCHEMBL3840479 | 0.77 | KDM4E (0.56) | ALDH1A1SLC6A4SLC6A3KDRHTR1A | |
| Hydrochloric Acid SCHEMBL4873626 | 0.76 | KDM4E (0.55) | ALDH1A1SLC6A4SLC6A3KDRHTR1A | |
| SCHEMBL15340905 | 0.76 | KMT2A (0.64) | ALDH1A1KDRCYP3A4CYP2D6MAPT | |
| SCHEMBL4875267 | 0.76 | ALDH1A1 (0.79) | ALDH1A1SLC6A4SLC6A3KDRCYP3A4 | |
| SCHEMBL21159094 | 0.74 | POLB (0.57) | ALDH1A1SLC6A4SLC6A3HTR1ACYP3A4 | |
| SCHEMBL20154465 | 0.74 | ROCK2 (0.50) | CYP3A4ROCK2CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL4874422 | 0.73 | KMT2A (0.66) | ALDH1A1MAPK1MEN1KMT2AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326710-B2 | Aralkyl formyl-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2008-02-05 | — | — | US | disclosed |
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2005-07-14 | — | — | US | disclosed |
| EP-1553092-A1 | ARALKYL FORMYL-ALKYL PIPERAZINE DERIVATIVES AND THEIR USES AS CEREBRAL NERVE PROTECTIVE AGENT | Shanghai Institute of Pharmaceutical Industry (CN) | 2005-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | GAP43, FABP7, AGK | ALDH1A1 1828/4885SLC6A4 3781/4885SLC6A3 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.