Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156033 | 1.00 | MMP8 (0.51) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL4881723 | 1.00 | MMP8 (0.51) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL4881722 | 1.00 | MMP8 (0.51) | MMP8PIN1MEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL4881666 | 0.98 | PIN1 (0.50) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL4450071 | 0.86 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL5652736 | 0.84 | MMP8 (0.47) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL16746620 | 0.84 | NPC1 (0.50) | NPC1SMN1; SMN2TSHRPOLB | |
| SCHEMBL5651686 | 0.84 | MMP8 (0.47) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL27813870 | 0.83 | MMP8 (0.51) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL23342965 | 0.82 | MMP8 (0.54) | MMP8PIN1MEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249310-A1 | Process For the Preparation of (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionamide and (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionic Acid Alkyl Ester | DSM IP ASSETS B.V. (NL) | 2008-10-09 | — | — | US | disclosed |
| EP-1831150-A1 | PROCESS FOR THE PREPARATION OF (2R, 3R)-2-HYDROXY-3-AMINO-3-ARYL-PROPIONAMIDE AND (2R, 3R)-2-HYDROXY-3-AMINO-3-ARYL-PROPIONIC ACID ALKYL ESTER | DSMIP Assets B.V. (NL) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006008170-A1 | PROCESS FOR THE PREPARATION OF (2R, 3R)-2-HYDROXY-3-AMINO-3-ARYL-PROPIONAMIDE AND (2R, 3R)-2-HYDROXY-3-AMINO-3-ARYL-PROPIONIC ACID ALKYL ESTER | DSM IP ASSETS B.V. (NL) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249310-A1 | Process For the Preparation of (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionamide and (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionic Acid Alkyl Ester | GRHPR, B3GAT3, HCAR3 | MMP8 4427/4885PIN1 1434/4885MEN1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.