Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.44 |
| ▸ | CHRNG | P07510 | 3/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.44 |
| ▸ | CHRND | Q07001 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18390264 | 0.84 | CHRM1 (0.65) | CHRM1MAOBALDH1A1KMT2ACYP3A4 | |
| SCHEMBL4818799 | 0.82 | CYP2D6 (0.67) | LMNACHRM1MAOBALDH1A1CYP3A4 | |
| SCHEMBL1714913 | 0.82 | SLC6A2 (0.50) | LMNAMAOBALDH1A1KMT2ACYP3A4 | |
| SCHEMBL20353685 | 0.81 | CHRM1 (0.51) | CHRM1MAOBALDH1A1KMT2ACYP3A4 | |
| SCHEMBL29522101 | 0.77 | CHRM1 (0.63) | CHRM1CYP3A4TSHRSLC6A3CYP2D6 | |
| SCHEMBL18390258 | 0.77 | CHRM1 (0.63) | CHRM1CYP3A4TSHRSLC6A3CYP2D6 | |
| SCHEMBL11037118 | 0.77 | SLC6A2 (0.67) | LMNAMAOBALDH1A1KMT2ACYP3A4 | |
| SCHEMBL28360223 | 0.77 | SLC6A2 (0.67) | LMNAMAOBALDH1A1KMT2ACYP3A4 | |
| SCHEMBL3838189 | 0.77 | KMT2A (0.61) | LMNAALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL22812221 | 0.77 | CHRM1 (0.50) | LMNACHRM1ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326710-B2 | Aralkyl formyl-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2008-02-05 | — | — | US | claimed |
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2005-07-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | GAP43, FABP7, AGK | CES2 1536/4885LMNA 1002/4885CES1 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.