Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.50 |
| ▸ | CHRNG | P07510 | 4/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.50 |
| ▸ | CHRND | Q07001 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360223 | 0.84 | SLC6A2 (0.67) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL11037118 | 0.84 | SLC6A2 (0.67) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL4818799 | 0.83 | CYP2D6 (0.67) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL1072701 | 0.83 | SLC6A2 (0.69) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL22614730 | 0.83 | SLC6A2 (0.65) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL28057449 | 0.83 | SLC6A2 (0.65) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL4874415 | 0.82 | CES2 (0.50) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL10728832 | 0.81 | SLC6A2 (0.68) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| Bromide SCHEMBL13729160 | 0.81 | SLC6A2 (0.68) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL321368 | 0.80 | ALDH1A1 (0.67) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
| EP-1817282-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | AstraZeneca AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056752-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | PAOX, PCCA, PAH | SLC6A2 422/4885SLC6A3 779/4885CHRNB4 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.