SCHEMBL487469

SCHEMBL487469

C=C(C)c1ccccc1C=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 4/20 0.46
TSHR P16473 1/20 0.46
TRIM24 O15164 1/20 0.46
TRIM33 Q9UPN9 1/20 0.46
ERN1 O75460 4/20 0.43
TLR2 O60603 1/20 0.41
TLR1 Q15399 1/20 0.41
TLR6 Q9Y2C9 1/20 0.41
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SRC P12931 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12138436 0.83 ERN1 (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL1484113 0.80 LMNA (0.52) LMNAKMT2AMEN1THRBBLM
SCHEMBL489258 0.80 ALDH1A1 (0.43) LMNAKMT2AMEN1ALDH1A1TSHR
SCHEMBL8385938 0.80 LMNA (0.52) LMNAKMT2AMEN1THRBBLM
SCHEMBL10054771 0.78 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL10415655 0.78 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL8712394 0.78 RAB9A (0.33) LMNAKMT2AMEN1ALDH1A1RAB9A
Benzene SCHEMBL28952313 0.78 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL10414731 0.78 LMNA (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL19917313 0.78 KMT2A (0.44) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3962863-B1 METHOD FOR THE GRAM-SCALE PREPARATION OF CUBIC FERRITE NANOCRYSTALS FOR BIOMEDICAL APPLICATIONS FONDAZIONE ST ITALIANO TECNOLOGIA (IT) 2024-04-24 EP claimed
EP-3144139-B1 NON-FLAMMABLE SHEET AND PRODUCTION METHOD THEREFOR TOPPAN PRINTING CO LTD (JP) 2021-06-23 EP disclosed
CN-106660306-B Incombustible sheet and method for producing same 凸版印刷株式会社 2020-01-21 CN disclosed
US-9914724-B2 C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof Shanghai De Novo Pharmatech Co., Ltd. (CN) 2018-03-13 US disclosed
US-9914724-B2 C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof Shanghai De Novo Pharmatech Co., Ltd. (CN) 2018-03-13 US disclosed
US-9914724-B2 C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof Shanghai De Novo Pharmatech Co., Ltd. (CN) 2018-03-13 US disclosed
EP-3144139-A1 NON-FLAMMABLE SHEET AND PRODUCTION METHOD THEREFOR Toppan Printing Co., Ltd. (JP) 2017-03-22 EP disclosed
US-20170056924-A1 NONFLAMMABLE SHEET AND METHOD FOR MANUFACTURING THE SAME TOPPAN PRINTING CO., LTD. (JP) 2017-03-02 US disclosed
EP-3133071-A1 C-ARYL INDICAN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USES THEREOF Shanghai De Novo Pharmatech Co Ltd. (CN) 2017-02-22 EP disclosed
EP-3133071-A1 C-ARYL INDICAN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USES THEREOF Shanghai De Novo Pharmatech Co Ltd. (CN) 2017-02-22 EP disclosed
EP-1507829-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA Nippon Shokubai Co., Ltd. (JP) 2005-02-23 EP disclosed
EP-0824127-B1 Water-type dispersion composition JSR CORP (JP) 2004-07-14 EP disclosed
US-6726997-B2 WWATERPROOF, HARDNESS, RATION TRANSPARENT; PROTECTIVE COATINGS JSR CORPORATION (JP) 2004-04-27 US disclosed
US-6660394-B1 Siloxane-vinyl copolymer, oxazoline crosslinker and organo-metallic betaketone or multifunctional hydrazine; rapid low temperature curing; water, weather, chemical, acid, alkali and wear resistance; durable adhesion JSR CORPORATION (JP) 2003-12-09 US disclosed
WO-2003099934-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA NIPPON SHOKUBAI CO., LTD. (JP) 2003-12-04 WO disclosed
US-20030073779-A1 Aqueous dispersion and coated product JSR CORPORATION (JP) 2003-04-17 US disclosed
EP-1256611-A2 Aqueous dispersion and coated product JSR Corporation (JP) 2002-11-13 EP disclosed
EP-1106661-A2 Coating composition and hardened film obtained therefrom JSR Corporation (JP) 2001-06-13 EP disclosed
US-5905109-A HYDROLYSIS AND CONDENSATION TO FORM POLYMERS WITH CATALYSTS JSR CORPORATION (JP) 1999-05-18 US disclosed
EP-0824127-A2 Water-type dispersion composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-02-18 EP disclosed