Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405011 | 0.87 | CA1 (0.58) | PPARGCA2CA1ANPEPALOX15 | |
| SCHEMBL404683 | 0.87 | CA1 (0.58) | PPARGCA2CA1ANPEPALOX15 | |
| SCHEMBL404729 | 0.85 | PPARG (0.49) | PPARGMLYCD | |
| SCHEMBL13654310 | 0.85 | PPARG (0.49) | PPARGMLYCD | |
| SCHEMBL403847 | 0.85 | PPARG (0.49) | PPARGMLYCD | |
| SCHEMBL399644 | 0.83 | CA1 (0.54) | PPARGCA2CA1NPSR1ANPEP | |
| SCHEMBL403777 | 0.83 | MMP2 (0.61) | PPARGMMP2MMP9MMP12ADAM17 | |
| SCHEMBL1096818 | 0.83 | ANPEP (0.56) | PPARGCA2CA1ANPEP | |
| SCHEMBL1105587 | 0.83 | MMP2 (0.61) | PPARGMMP2MMP9MMP12ADAM17 | |
| SCHEMBL5450568 | 0.83 | CA2 (0.49) | PPARGCA2CA1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | PPARG 1875/4885CA2 3457/4885CA1 4246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.