Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19067391 | 0.85 | CTDSP1 (0.53) | PLAUALDH1A1ALOX12HTTTYR | |
| SCHEMBL10224685 | 0.82 | HDAC4 (0.57) | PLAUALDH1A1HPGDALOX15HDAC4 | |
| SCHEMBL9179432 | 0.80 | UGT2B7 (0.44) | ALDH1A1ALOX12HTTTYRKDM4E | |
| SCHEMBL12232848 | 0.78 | NQO2 (0.55) | ALDH1A1ALOX12HTTTYRKDM4E | |
| SCHEMBL30876285 | 0.78 | UGT2B7 (0.42) | ALDH1A1ALOX12HTTTYRKDM4E | |
| SCHEMBL8781801 | 0.78 | UGT2B7 (0.42) | ALDH1A1ALOX12HTTTYRKDM4E | |
| SCHEMBL7927384 | 0.78 | CYP1A2 (0.59) | ALDH1A1ALOX12HTTTYRKDM4E | |
| SCHEMBL10238671 | 0.77 | CYP1A2 (0.48) | ALDH1A1ALOX12HTTTYRKDM4E | |
| SCHEMBL14572010 | 0.77 | ALDH1A1 (0.48) | PLAUALDH1A1ALOX12HTTKDM4E | |
| SCHEMBL598202 | 0.76 | AKR1B1 (0.54) | ALDH1A1MAPTHPGDTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250314-A1 | COMPOSITION FOR FORMING A COATING FILM FOR REMOVING FOREIGN MATTERS | NISSAN CHEMICAL CORPORATION (JP) | 2023-08-10 | — | — | US | disclosed |
| US-20210171461-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION | 2021-06-10 | — | — | US | disclosed |
| US-20130338363-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-12-19 | — | — | US | disclosed |
| US-8541532-B2 | Silane compound, production method thereof, and resin composition containing silane compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| CN-102337005-B | Resin composition, method of its composition, and cured formulation | NIPPON CATALYTIC CHEM IND | 2013-06-12 | — | — | CN | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| EP-2180019-B1 | Resin composition, method of its composition, and cured formulation | NIPPON CATALYTIC CHEM IND (JP) | 2012-02-01 | — | — | EP | disclosed |
| CN-102337005-A | Resin composition, method of its composition, and cured formulation | NIPPON CATALYTIC CHEM IND | 2012-02-01 | — | — | CN | disclosed |
| CN-101831142-B | Resin composition, preparation method thereof, and cured formulation | NIPPON SHOKUBAI CO.,LTD. (JP) | 2012-02-01 | — | — | CN | disclosed |
| US-7994167-B2 | Pentafluorosulphanyl-substituted compound and its use for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| CN-101035866-A | Resin composition for optical packaging material, method for producing the same, optical packaging material, optical packaging member, and optical module | NIPPON CATALYTIC CHEM IND (JP) | 2007-09-12 | — | — | CN | disclosed |
| WO-2007027855-A2 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC. | 2007-03-01 | — | — | US | disclosed |
| WO-2006038735-A1 | RESIN COMPOSITION FOR OPTICAL PACKAGING MATERIAL AND PROCESS FOR PREPARING THE SAME, AND OPTICAL PACKAGING MATERIAL, OPTICAL PACKAGING COMPONENT, AND OPTICAL MODULE | NIPPON SHOKUBAI CO., LTD. (JP) | 2006-04-13 | — | — | WO | disclosed |
| EP-1626065-A1 | Resin composition, method of its composition, and cured formulation | Nippon Shokubai Co., Ltd. (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-20060029811-A1 | mixing a phenolic compound containing the inorganic microfine particle(SiO2) and a compound containing at least one of the glycidyl group and/or an epoxy group containing the inorganic microfine particle; fireproofing; good mechanical properties; heat resistance; automobiles, construction, electronics | NIPPON SHOKUBAI CO., LTD. (JP) | 2006-02-09 | — | — | US | disclosed |
| CN-1730548-A | Resin composition, method for producing same, and cured product | NIPPON CATALYTIC CHEM IND (JP) | 2006-02-08 | — | — | CN | disclosed |
| US-5003113-A | Process of producing isopropylnaphthols | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0370729-A1 | Process for producing isopropylnaphthols | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| EP-0308133-A1 | A method of oxidising secondary alkyl substituted naphthalenes | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | BRAF, RAF1, ARAF | PLAU 2648/4885ALDH1A1 1842/4885ALOX12 3532/4885 |
| US-20130338363-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | ZYX, NOX3, NOXO1 | PLAU 4000/4885ALDH1A1 1943/4885ALOX12 76/4885 |
| US-20210171461-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | PLAU 303/4885ALDH1A1 4709/4885ALOX12 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.