Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CES1 | P23141 | 1/20 | 0.67 |
| ▸ | ERCC5 | P28715 | 4/20 | 0.63 |
| ▸ | FEN1 | P39748 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707718 | 0.88 | HAO1 (0.68) | MAPTMAPK1HPGDKMT2AMEN1 | |
| Benzene SCHEMBL11711818 | 0.84 | HAO1 (0.59) | MAPTMAPK1HPGDKMT2AMEN1 | |
| SCHEMBL11714725 | 0.84 | ERCC5 (0.71) | MAPTMAPK1HPGDKMT2AMEN1 | |
| SCHEMBL30951020 | 0.83 | MAOA (0.50) | MAPTMAPK1HPGDKMT2AMEN1 | |
| SCHEMBL11705647 | 0.82 | ERCC5 (0.67) | MAPTKMT2AMEN1KDM4EALOX15 | |
| SCHEMBL10649708 | 0.82 | HAO1 (0.61) | MAPTMAPK1HPGDKMT2AMEN1 | |
| SCHEMBL10645841 | 0.82 | NPC1 (0.63) | MAPTMAPK1HPGDKMT2AMEN1 | |
| SCHEMBL11709368 | 0.82 | PLOD2 (0.55) | MAPTMAPK1HPGDKMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.81 | MEN1 (1.00) | MAPTMAPK1HPGDKMT2AMEN1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.81 | MEN1 (1.00) | MAPTMAPK1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368458-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| US-7368458-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| US-7368458-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| WO-2006076597-A1 | BICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060155126-A1 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2006-07-13 | — | — | US | disclosed |
| EP-0164101-B1 | BENZOYLPROPIONIC ACID DERIVATIVES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-09-07 | — | — | EP | disclosed |
| US-4600540-A | &MMUNOLOGY, ANTIARTHRITIC, ANTICARCINOGENIC, BACTERICIDES, ASTHMA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-07-15 | — | — | US | disclosed |
| EP-0164101-A2 | Benzoylpropionic acid derivatives, their use and pharmaceutical compositions | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-12-11 | — | — | EP | disclosed |
| US-4058558-A | 2-METHYLENE-4-OXO-4(4'-ORTHO-CHLOROPHENYLPHENYL)BUTYRIC ACID | PIERRE FABRE S.A. (FR) | 1977-11-15 | — | — | US | disclosed |
| US-4008323-A | Method of reducing cholesterol using certain aromatic keto acids | PIERRE FABRE S.A. (FR) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155126-A1 | Bicyclic heterocycles as cannabinoid receptor modulators | CNR1, CNR2, GPR18 | MAPT 4202/4885MAPK1 2583/4885HPGD 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.