Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19072274 | 0.83 | SMN1; SMN2 (0.40) | PIN1ALDH1A1MAPTHTTGAA | |
| SCHEMBL487814 | 0.83 | PIN1 (0.39) | PIN1ALDH1A1MAPTGPR35HTT | |
| SCHEMBL27324878 | 0.83 | PIN1 (0.39) | PIN1ALDH1A1MAPTGPR35GAA | |
| SCHEMBL27885519 | 0.82 | CYP1A2 (0.42) | PIN1MAPTVCAM1MEN1KMT2A | |
| SCHEMBL6384034 | 0.81 | PIN1 (0.38) | PIN1ALDH1A1MAPTGPR35GAA | |
| SCHEMBL27743531 | 0.80 | PIN1 (0.40) | PIN1ALDH1A1MAPTGPR35GAA | |
| SCHEMBL3326111 | 0.79 | TDP1 (0.40) | PIN1ALDH1A1MAPTGAATSHR | |
| SCHEMBL5037042 | 0.79 | FBP1 (0.42) | PIN1ALDH1A1MAPTHTTMAPK1 | |
| SCHEMBL5033869 | 0.78 | PIN1 (0.62) | PIN1ALDH1A1MAPTGAAVCAM1 | |
| SCHEMBL28018377 | 0.76 | PIN1 (0.40) | PIN1MAPTVCAM1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049488-B1 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2015-12-09 | — | — | EP | disclosed |
| EP-2004636-B1 | Substituted enaminocarbonyl compounds used as insecticides | BAYER IP GMBH (DE) | 2015-04-22 | — | — | EP | disclosed |
| US-20140113824-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| EP-2707373-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | Bayer Intellectual Property GmbH (DE) | 2014-03-19 | — | — | EP | disclosed |
| CN-101460502-B | Bicyclic enamino(thio)carbonyl compounds | BAYER CROPSCIENCE AG | 2013-07-17 | — | — | CN | disclosed |
| EP-2021344-B1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-05-08 | — | — | EP | disclosed |
| EP-2004606-B1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2012152741-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-11-15 | — | — | WO | disclosed |
| CN-101454316-B | Substituted enaminocarbonyl compounds for use as pesticides | BAYER CROPSCIENCE AG | 2012-08-15 | — | — | CN | disclosed |
| US-8138350-B2 | N′-cyano-N-halogenalkylimidamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20090181947-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-07-16 | — | — | US | disclosed |
| CN-101460502-A | Bicyclic enamino(thio)carbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2009-06-17 | — | — | CN | disclosed |
| CN-101454316-A | Substituted enaminocarbonyl compounds for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-06-10 | — | — | CN | disclosed |
| EP-2049488-A2 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2009-04-22 | — | — | EP | disclosed |
| CN-101415682-A | Substituted enaminocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2009-04-22 | — | — | CN | disclosed |
| EP-2021344-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | Bayer CropScience AG (DE) | 2009-02-11 | — | — | EP | disclosed |
| EP-2004606-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | Bayer CropScience AG (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008009360-A2 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007115643-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007115647-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181947-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | TARS2, TBCA, DDT | PIN1 188/4885ALDH1A1 2672/4885MAPT 1768/4885 |
| US-20140113824-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BROX, BOLA2; BOLA2B, CAT | PIN1 2489/4885ALDH1A1 1780/4885MAPT 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.