Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4613473 | 0.81 | PPARG (0.60) | MAPTPPARGPTPN1KDM4ECA1 | |
| SCHEMBL15528187 | 0.77 | CA1 (0.54) | MAPTPPARGPTPN1L3MBTL1GAA | |
| SCHEMBL9595 | 0.77 | CA1 (0.54) | MAPTPPARGPTPN1L3MBTL1GAA | |
| SCHEMBL8612 | 0.77 | CA1 (0.56) | MAPTPPARGPTPN1L3MBTL1KDM4E | |
| SCHEMBL10623072 | 0.76 | KDM4E (0.63) | MAPTPPARGPTPN1GAAKDM4E | |
| SCHEMBL15527966 | 0.74 | CA1 (0.56) | MAPTPPARGPTPN1L3MBTL1GAA | |
| SCHEMBL8733 | 0.74 | CA1 (0.59) | MAPTGAAKDM4EHPGDALDH1A1 | |
| SCHEMBL20696670 | 0.72 | CYP4F2 (0.52) | MAPTCYP4F2CYP4A11GAAKDM4E | |
| SCHEMBL9311 | 0.72 | CA1 (0.56) | MAPTPTPN1L3MBTL1GAAKDM4E | |
| SCHEMBL16724774 | 0.72 | RAB9A (0.51) | MAPTCYP4F2CYP4A11L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368434-B2 | Compounds useful for the inhibition of ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 2008-05-06 | — | — | US | disclosed |