SCHEMBL4613473

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8612	0.90	CA1 (0.56)	PPARGPTPN1CA1CA2MAPT
	SCHEMBL9595	0.84	CA1 (0.54)	PPARGPTPN1CA1CA2MAPT
	SCHEMBL15528187	0.84	CA1 (0.54)	PPARGPTPN1CA1CA2MAPT
	SCHEMBL8733	0.84	CA1 (0.59)	CA1CA2MAPTEYA3CYP2C9
	SCHEMBL15527966	0.81	CA1 (0.56)	PPARGPTPN1CA1CA2MAPT
	SCHEMBL9311	0.81	CA1 (0.56)	PTPN1CA1CA2MAPTABCG2
	SCHEMBL7855340	0.81	PTPN1 (0.82)	PPARGPTPN1MAPTEYA3
	SCHEMBL4875780	0.81	MAPT (0.51)	PPARGPTPN1CA1CA2MAPT
	SCHEMBL10716	0.81	MAPK14 (0.53)	PPARGPTPN1CA1CA2MAPT
	SCHEMBL18407427	0.80	EYA3 (0.50)	PPARGPTPN1MAPTEYA3CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.