Sugi Predict

Sugi Predict / Compounds / SCHEMBL4876557

SCHEMBL4876557

SCHEMBL4876557

CC(=O)N(c1ccccc1)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.61
▸ LMNA P02545 3/20 0.61
▸ TP53 P04637 1/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ PKM P14618 1/20 0.51
▸ MLYCD O95822 1/20 0.51
▸ TRPM8 Q7Z2W7 2/20 0.50
▸ MAPT P10636 1/20 0.48
▸ APAF1 O14727 1/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ KMT2A Q03164 1/20 0.44
▸ CHRM2 P08172 1/20 0.43
▸ CHRM1 P11229 1/20 0.43
▸ CHRM3 P20309 1/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ GLA P06280 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ CES2 O00748 1/20 0.41
▸ CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2543696 0.84 ALDH1A1 (0.63) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL5079915 0.84 ALDH1A1 (0.63) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL1061794 0.83 LMNA (0.49) ALDH1A1LMNATP53SMN1; SMN2PKM
SCHEMBL2968427 0.83 LMNA (0.49) ALDH1A1LMNATP53SMN1; SMN2PKM
SCHEMBL11249889 0.83 LMNA (0.49) ALDH1A1LMNATP53SMN1; SMN2PKM
SCHEMBL11261967 0.83 LMNA (0.49) ALDH1A1LMNATP53SMN1; SMN2PKM
SCHEMBL10398307 0.83 ALDH1A1 (0.49) ALDH1A1LMNATP53SMN1; SMN2PKM
SCHEMBL28788459 0.83 ALDH1A1 (0.49) ALDH1A1LMNATP53SMN1; SMN2PKM
SCHEMBL5932410 0.83 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL8040628 0.82 ALDH1A1 (0.47) ALDH1A1LMNATP53SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442693-B2 Diazepine compounds as ligands of the melanocortin 1 and/or 4 receptors SMITHKLINE BEECHAM CORPORATION (US) 2008-10-28 — — US claimed
CN-1509141-A Herbicides based on substituted aryl ketones �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-06-30 — — CN claimed
EP-1423005-A1 HERBICIDAL MIXTURES BASED ON SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 — — EP claimed
WO-2003020033-A1 HERBICIDAL MIXTURES BASED ON SUBSTITUTED ARYL KETONES BAYER CROPSCIENCE AG (DE) 2003-03-13 — — WO claimed
WO-2003000058-A1 SELECTIVE HERBICIDES BASED ON PYRIMIDINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-01-03 — — WO claimed
CN-1047958-A The herbicidal composition and the antidotes composition of detoxifcation NITROKEMIA IPARTELEPEK (HU) 1990-12-26 — — CN claimed
EP-0088066-B1 3,5-BIS (TRIFLUOROMETHYL) PHENOXY CARBOXYLIC ACIDS AND DERIVATIVES THEREOF MONSANTO COMPANY (US) 1985-04-03 — — EP claimed
CN-117024295-B Photo-induced amide dealkylation method and application thereof 广州中医药大学(广州中医药研究院) 2025-06-13 — — CN disclosed
CN-117024295-A Photo-induced amide dealkylation method and application thereof 广州中医药大学(广州中医药研究院) 2023-11-10 — — CN disclosed
EP-3235799-B1 OXIME COMPOUND AND HERBICIDE NISSAN CHEMICAL CORP (JP) 2022-02-23 — — EP disclosed
US-11000033-B2 Ketone or oxime compound, and herbicide NISSAN CHEMICAL CORPORATION (JP) 2021-05-11 — — US disclosed
US-20190053488-A1 KETONE OR OXIME COMPOUND, AND HERBICIDE NISSAN CHEMICAL CORPORATION (JP) 2019-02-21 — — US disclosed
US-20170347647-A1 KETONE OR OXIME COMPOUND, AND HERBICIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-12-07 — — US disclosed
EP-0929221-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AG (DE) 1999-07-21 — — EP disclosed
EP-0869715-A1 NEW HERBICIDAL COMPOSITIONS RHONE-POULENC AGRICULTURE LTD. (GB) 1998-10-14 — — EP disclosed
WO-1998012923-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-02 — — WO disclosed
WO-1997023134-A1 NEW HERBICIDAL COMPOSITIONS RHONE-POULENC AGRICULTURE LTD. (GB) 1997-07-03 — — WO disclosed
CN-1120843-A Derivatives of class 1, 5-benzodiazepine * having CCK antagonistic or agonistic activity GLAXO INC (US) 1996-04-17 — — CN disclosed
CN-1047958-A The herbicidal composition and the antidotes composition of detoxifcation NITROKEMIA IPARTELEPEK (HU) 1990-12-26 — — CN disclosed
EP-0088066-B1 3,5-BIS (TRIFLUOROMETHYL) PHENOXY CARBOXYLIC ACIDS AND DERIVATIVES THEREOF MONSANTO COMPANY (US) 1985-04-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11000033-B2 Ketone or oxime compound, and herbicide OR10J3, CYP1B1, CBR3 ALDH1A1 493/4885LMNA 4562/4885TP53 3626/4885
US-20190053488-A1 KETONE OR OXIME COMPOUND, AND HERBICIDE OR10J3, CYP1B1, CBR3 ALDH1A1 517/4885LMNA 4561/4885TP53 3666/4885
US-20170347647-A1 KETONE OR OXIME COMPOUND, AND HERBICIDE OR10J3, CYP1B1, CBR3 ALDH1A1 517/4885LMNA 4561/4885TP53 3666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.