Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | CBX7 | O95931 | 2/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878179 | 0.95 | PIK3CA (0.42) | ACHEL3MBTL1PIK3CAMTORCBX7 | |
| SCHEMBL4870899 | 0.92 | ACHE (0.40) | ACHEL3MBTL1PIK3CAMTORCBX7 | |
| SCHEMBL4866875 | 0.90 | ALDH1A1 (0.39) | L3MBTL1PIK3CAMTORALDH1A1KDM4E | |
| SCHEMBL4877773 | 0.89 | CBX7 (0.38) | ACHEL3MBTL1PIK3CAMTORCBX7 | |
| SCHEMBL4877137 | 0.89 | CBX7 (0.39) | ACHEPIK3CAMTORCBX7CDYL2 | |
| SCHEMBL4873226 | 0.89 | CBX7 (0.39) | ACHEPIK3CAMTORCBX7CDYL2 | |
| SCHEMBL4877171 | 0.89 | PIK3CA (0.43) | ACHEPIK3CAMTORCBX7CDYL2 | |
| SCHEMBL4868467 | 0.88 | KDM4E (0.44) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4874715 | 0.88 | BRD4 (0.38) | ACHEPIK3CAMTORCBX7CDYL2 | |
| SCHEMBL4874071 | 0.88 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | ACHE 2191/4885L3MBTL1 3239/4885PIK3CA 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.