SCHEMBL3414901

SCHEMBL3414901

CCC(C(=O)O)c1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 13/20 0.54
HTR1A P08908 1/20 0.51
ADRA1A P35348 1/20 0.51
DDAH1 O94760 1/20 0.50
HSP90AA1 P07900 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
CACNA1B Q00975 1/20 0.49
APBA1 Q02410 1/20 0.49
FAAH O00519 6/20 0.48
PKM P14618 1/20 0.46
MAPK1 P28482 1/20 0.46
AKR1C3 P42330 3/20 0.43
AKR1C2 P52895 3/20 0.43
AKR1C1 Q04828 1/20 0.43
PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2348816 0.86 MGLL (0.53) MGLLHTR1AADRA1ADDAH1HSP90AA1
SCHEMBL7633213 0.81 MGLL (0.63) MGLLDDAH1HSP90AA1NPSR1TDP1
SCHEMBL1574429 0.80 AKR1C3 (0.58) HTR1AADRA1AALDH1A1AKR1C3AKR1C2
SCHEMBL31207305 0.80 HTR1A (0.64) HTR1AADRA1AALDH1A1HPGD
SCHEMBL27264219 0.80 HTR1A (0.64) HTR1AADRA1AALDH1A1HPGD
SCHEMBL6788274 0.78 MGLL (0.65) MGLLDDAH1HSP90AA1NPSR1TDP1
SCHEMBL10780780 0.77 MGLL (0.65) MGLLADRA1ADDAH1HSP90AA1NPSR1
SCHEMBL28308627 0.77 MGLL (0.59) MGLLDDAH1HSP90AA1NPSR1TDP1
SCHEMBL2125273 0.77 ALDH1A1 (0.46) MGLLHTR1AADRA1ADDAH1HSP90AA1
SCHEMBL19134296 0.76 MGLL (0.67) MGLLHSP90AA1NPSR1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712423-B2 Methods and compositions for modifying mucous membranes ABBOTT NICHOLAS L (US) 2023-08-01 US disclosed
WO-2013130684-A1 XTEN-FOLATE CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME AMUNIX OPERATING INC. (US) 2013-09-06 WO disclosed
EP-2262474-A2 METHODS AND COMPOSITIONS FOR WOUND HEALING Mcanulty, Jonathan (US) 2010-12-22 EP disclosed
WO-2009097508-A2 METHODS AND COMPOSITIONS FOR WOUND HEALING MCANULTY, JONATHAN (US) 2009-08-06 WO disclosed
US-20080119421-A1 Process for treating a biological organism TECHNOLOGY INNOVATIONS, LLC 2008-05-22 US disclosed
US-20050249667-A1 Process for treating a biological organism TECHNOLOGY INNOVATIONS, LLC 2005-11-10 US disclosed
EP-0983095-B1 PEPTIDE-COATED IMPLANTS AND METHODS FOR PRODUCING THEM BIOMET DEUTSCHLAND GMBH (DE) 2004-09-29 EP disclosed
EP-0983095-A2 PEPTIDE-COATED IMPLANTS AND METHODS FOR PRODUCING SAME MERCK PATENT GmbH (DE) 2000-03-08 EP disclosed
WO-1999059643-A2 LIPOSOMAL DELIVERY COMPLEX SDG, INC. (US) 1999-11-25 WO disclosed
WO-1998052619-A2 PEPTIDE-COATED IMPLANTS AND METHODS FOR PRODUCING SAME MERCK PATENT GMBH (DE) 1998-11-26 WO disclosed
US-5411730-A Iron oxide and dextran, delivering to tumor and heating with radio frequency RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-05-02 US disclosed
US-5399331-A Drug delivery, medical diagnosis THE LIPOSOME COMPANY, INC. (US) 1995-03-21 US disclosed
EP-0414741-B1 FURTHER IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS CANCER RES CAMPAIGN TECH (GB) 1995-03-15 EP disclosed
EP-0641388-A1 ION-CAPTURE ASSAYS USING A BINDING MEMBER CONJUGATED TO CARBOXYMETHYLAMYLOSE ABBOTT LABORATORIES (US) 1995-03-08 EP disclosed
EP-0586605-A1 REAGENTS AND METHODS FOR PERFORMING TWO-STEP ION-CAPTURE BINDING ASSAYS ABBOTT LABORATORIES (US) 1994-03-16 EP disclosed
WO-1992021772-A1 ION-CAPTURE ASSAYS USING A BINDING MEMBER CONJUGATED TO CARBOXYMETHYLAMYLOSE ABBOTT LABORATORIES (US) 1992-12-10 WO disclosed
WO-1992021770-A1 REAGENTS AND METHODS FOR PERFORMING TWO-STEP ION-CAPTURE BINDING ASSAYS ABBOTT LABORATORIES (US) 1992-12-10 WO disclosed
WO-1991000289-A2 TARGETED LIPOSOMES AND METHODS FOR LIPOSOME-PROTEIN COUPLING THE LIPOSOME COMPANY, INC. (US) 1991-01-10 WO disclosed
EP-0398305-A2 Anthracycline conjugates having a novel linker and methods for their production Bristol-Myers Squibb Company (US) 1990-11-22 EP disclosed
EP-0328147-A2 Anthracycline immunoconjugates having a novel linker and methods for their production Bristol-Myers Squibb Company (US) 1989-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119421-A1 Process for treating a biological organism BUB1, BOD1L1, BUB1B MGLL 4491/4885HTR1A 4271/4885ADRA1A 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.