Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876702 | 0.85 | MAPT (0.49) | LMNAMAPTALDH1A1GSK3AGSK3B | |
| SCHEMBL1743735 | 0.76 | ALDH1A1 (0.39) | MAPTALDH1A1NPC1SMN1; SMN2GAA | |
| SCHEMBL370888 | 0.75 | L3MBTL1 (0.46) | LMNAMAPTALDH1A1GSK3AGSK3B | |
| SCHEMBL5520026 | 0.72 | ALOX5 (0.47) | LMNAMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL14108630 | 0.72 | LMNA (0.53) | LMNAMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL2690687 | 0.71 | PTPN11 (0.55) | LMNAMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL1930792 | 0.71 | GAA (0.46) | LMNAMAPTALDH1A1GSK3AGSK3B | |
| SCHEMBL4397796 | 0.70 | SCD (0.44) | MAPTALDH1A1NPC1SMN1; SMN2GAA | |
| SCHEMBL29135461 | 0.70 | SAE1 (0.78) | LMNAMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9555500 | 0.70 | PTGDR2 (0.67) | ALDH1A1PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076771-A1 | Thrombopoietin Receptor Agonists | REITER LAWRENCE A | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076771-A1 | Thrombopoietin Receptor Agonists | MPL, THPO, TBXA2R | LMNA 2506/4885MAPT 4880/4885ALDH1A1 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.