Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161297 | 0.79 | ALDH1A1 (0.42) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL29001798 | 0.79 | ALDH1A1 (0.42) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL7237526 | 0.77 | KDM4E (0.40) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL27934781 | 0.76 | TDO2 (0.44) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL27945389 | 0.76 | ALDH1A1 (0.42) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL255914 | 0.76 | MAPK1 (0.56) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL16370004 | 0.76 | ALDH1A1 (0.39) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL21988636 | 0.73 | KDM4E (0.40) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL28294729 | 0.73 | MAPT (0.37) | NOTUMALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL28050904 | 0.72 | NOTUM (0.49) | NOTUMALDH1A1KDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919474-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE OF SAME AS PPAR RECEPTOR MODULATORS | Laboratoires Fournier S.A. (FR) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026104-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE OF SAME AS PPAR RECEPTOR MODULATORS | LABORATOIRES FOURNIER S.A. (FR) | 2007-03-08 | — | — | WO | disclosed |