Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618881 | 0.83 | LMNA (0.40) | LMNAPOLBNR3C1 | |
| SCHEMBL3619771 | 0.83 | NR1H4 (0.45) | LMNAPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL4884604 | 0.81 | POLB (0.49) | LMNAPOLBNR3C1NPC1RAB9A | |
| SCHEMBL3621078 | 0.81 | NAMPT (0.42) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4876097 | 0.80 | F10 (0.38) | LMNAPOLBNR3C1NPC1RAB9A | |
| SCHEMBL4881051 | 0.80 | RAB9A (0.38) | LMNANPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL3622624 | 0.79 | LMNA (0.35) | LMNAPOLBNR3C1NPC1RAB9A | |
| SCHEMBL3614731 | 0.79 | RAB9A (0.39) | LMNANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3613978 | 0.78 | GCGR (0.40) | NR3C1ALDH1A1GAAMAPTHTT | |
| SCHEMBL4880920 | 0.78 | SCN9A (0.38) | LMNANPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214533-A1 | Cyclic Iminocarbamates And Their Use | BAYER HEALTHCARE AG (DE) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214533-A1 | Cyclic Iminocarbamates And Their Use | F2, UQCRB, F12 | LMNA 66/4885POLB 433/4885NR3C1 3575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.