Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881051 | 0.86 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL3621276 | 0.83 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2NAMPTKMT2A | |
| SCHEMBL3619771 | 0.82 | NR1H4 (0.45) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4881687 | 0.82 | SIRT2 (0.37) | RAB9ANPC1SMN1; SMN2SIRT2NAMPT | |
| SCHEMBL3621078 | 0.82 | NAMPT (0.42) | RAB9ANPC1SMN1; SMN2NAMPTKMT2A | |
| SCHEMBL4880879 | 0.81 | RAB9A (0.37) | RAB9ANPC1SMN1; SMN2SIRT2KMT2A | |
| SCHEMBL4880731 | 0.81 | MAPT (0.36) | RAB9ANPC1SMN1; SMN2SIRT2KDM4E | |
| SCHEMBL4878081 | 0.80 | KMT2A (0.38) | RAB9ANPC1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL4880920 | 0.79 | SCN9A (0.38) | RAB9ANPC1SIRT2KMT2AMAPK1 | |
| SCHEMBL4878149 | 0.79 | LMNA (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | BAYER HEALTHCARE AG (DE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | PPOX, XDH, PNPO | RAB9A 3775/4885NPC1 2710/4885SMN1; SMN2 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.