Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28457606 | 0.90 | NOS3 (0.44) | ALDH1A1NPSR1FAAHNOS3NOS1 | |
| SCHEMBL27271477 | 0.86 | — | — | |
| SCHEMBL15512673 | 0.84 | ALDH1A1 (0.49) | ALDH1A1NPSR1EPHX1MAPTLMNA | |
| SCHEMBL17724885 | 0.79 | — | — | |
| SCHEMBL14776802 | 0.78 | GPR84 (0.47) | ALDH1A1HDAC11MAPTLMNATDP1 | |
| SCHEMBL11847360 | 0.78 | EPHX2 (0.37) | ALDH1A1NPSR1HDAC3HDAC4HDAC1 | |
| SCHEMBL8801947 | 0.77 | — | — | |
| SCHEMBL9679774 | 0.77 | — | — | |
| SCHEMBL11810464 | 0.77 | EPHX1 (0.50) | ALDH1A1NPSR1EPHX1CASP2ACHE | |
| SCHEMBL6692189 | 0.77 | EPHX1 (0.55) | EPHX1CASP2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214398-A1 | Herbicidal activities of combinations of sodium azide with sulfur containing and other deactivating compounds | AUBURN UNIVERSITY | 2008-09-04 | — | — | US | disclosed |
| EP-0004377-B1 | THIOCARBAMATE PREPARATION UTILIZING QUATERNARY AMMONIUM SALT CATALYSTS | STAUFFER CHEMICAL COMPANY (US) | 1982-03-17 | — | — | EP | disclosed |
| EP-0004377-A1 | Thiocarbamate preparation utilizing quaternary ammonium salt catalysts | STAUFFER CHEMICAL COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
| US-4147715-A | Thiocarbamate preparation utilizing quaternary ammonium salt catalysts | STAUFFER CHEMICAL COMPANY (US) | 1979-04-03 | — | — | US | disclosed |