⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679687 | 0.83 | MMP1 (0.38) | — | |
| SCHEMBL27271477 | 0.81 | — | — | |
| SCHEMBL9678864 | 0.79 | EPHX1 (0.44) | — | |
| SCHEMBL17724885 | 0.79 | — | — | |
| SCHEMBL4878677 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL8801947 | 0.77 | — | — | |
| SCHEMBL9678871 | 0.77 | CYP2C19 (0.45) | — | |
| SCHEMBL9679843 | 0.76 | — | — | |
| SCHEMBL8309477 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL9420088 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272063-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4863935-A | Mitomycin compounds having useful anti-tumor activity | KYOWA HAKKO KOGYO K.K. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0272063-A1 | Mitomycin derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-3985564-A | Photographic element and process for developing | EASTMAN KODAK COMPANY (US) | 1976-10-12 | — | — | US | disclosed |