Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM4B | O94953 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490421 | 0.80 | PARP10 (0.57) | L3MBTL1KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL14005203 | 0.79 | KMT2A (0.53) | L3MBTL1KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL14005183 | 0.79 | KDM4A (0.46) | L3MBTL1KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL6018082 | 0.78 | CXCR4 (0.49) | L3MBTL1POLBNPC1RAB9ALMNA | |
| SCHEMBL3314110 | 0.77 | L3MBTL1 (0.62) | L3MBTL1POLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29860055 | 0.77 | L3MBTL1 (0.62) | L3MBTL1POLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4743413 | 0.76 | SMN1; SMN2 (0.57) | L3MBTL1KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL18322326 | 0.76 | CYP1A2 (0.53) | LMNAKMT2ASMN1; SMN2MAPK14HDAC8 | |
| SCHEMBL1169765 | 0.76 | L3MBTL1 (0.57) | L3MBTL1POLBNPC1RAB9ALMNA | |
| SCHEMBL2947235 | 0.75 | ALDH1A1 (0.63) | L3MBTL1KDM4AKDM4BKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |