Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.45 |
| ▸ | PPIB | P23284 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949416 | 0.82 | NPSR1 (0.50) | SMN1; SMN2MAPTHTTNPSR1KMT2A | |
| SCHEMBL4936106 | 0.82 | HDAC1 (0.51) | HDAC6HDAC1EPHX2NR1H4HDAC10 | |
| SCHEMBL5611501 | 0.81 | CYP1A2 (0.46) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL31494698 | 0.80 | ALDH1A1 (0.52) | HDAC6HDAC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL407836 | 0.78 | L3MBTL1 (0.50) | TSHRCYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL11254594 | 0.77 | CES2 (0.52) | CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL6077891 | 0.77 | LMNA (0.46) | HDAC6HDAC1PPIBSMN1; SMN2EPHX2 | |
| Hydrochloric Acid SCHEMBL8355067 | 0.76 | ADRA2C (0.49) | TSHRCYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL4878707 | 0.76 | L3MBTL1 (0.47) | HDAC6SMN1; SMN2HDAC8LMNAMAPK14 | |
| Hydrochloric Acid SCHEMBL11834225 | 0.76 | CES2 (0.50) | CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016205566-A1 | FZD7 SPECIFIC ANTIBODIES AND VACCINES TO TREAT CANCER AND CONTROL STEM CELL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-22 | — | — | WO | disclosed |